ReviewCell2019
Toward a Common Coordinate Framework for the Human Body.
Review in Cell, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
69 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- Tissue and cellular spatiotemporal dynamics in colon aging.Nature biotechnology · 2026Article
- Cell shapes decode molecular phenotypes in image-based spatial proteomics.Cell systems · 2026Article
- 3D chromatin architecture-related genes orchestrate LUAD evolution and therapy resistance: insights from integrative machine learning and spatial single-cell mapping.Functional & integrative genomics · 2026Article
- An integrative spatial multi-omic workflow for unified analysis of tumor tissue.Cell reports methods · 2026Article
- Spatial architecture of development and disease.Nature reviews. Genetics · 2026Review
- An Interactive Brain Atlas of Knowledge.bioRxiv : the preprint server for biology · 2026Article
- Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function.Cell · 2025Review
- A multiscale vascular atlas of blood vessels supplying the urinary bladder of male and female mice.American journal of physiology. Renal physiology · 2025Article
- Integrating Spatially-Resolved Transcriptomics Data Across Tissues and Individuals: Challenges and Opportunities.Small methods · 2025Review
- Adhesion-Related Pathways and Functional Polarization of Astrocytes in Traumatic Brain Injury: Insights from Single-cell RNA Sequencing.Neuromolecular medicine · 2025Article
- Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas construction and usage.Nature methods · 2025Article
- Quantitative characterization of cell niches in spatially resolved omics data.Nature genetics · 2025Article
- Techniques and analytic workflow for spatial transcriptomics and its application to allergy and inflammation.The Journal of allergy and clinical immunology · 2025Review
- Mapping cells through time and space with moscot.Nature · 2025Article
- Article
- Review
- SpatialData: an open and universal data framework for spatial omics.Nature methods · 2025Article
- Article
- Search and match across spatial omics samples at single-cell resolution.Nature methods · 2024Article
9 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
Abstract
Understanding the genetic and molecular drivers of phenotypic heterogeneity across individuals is central to biology. As new technologies enable fine-grained and spatially resolved molecular profiling, we need new computational approaches to integrate data from the same organ across different individuals into a consistent reference and to construct maps of molecular and cellular organization at histological and anatomical scales. Here, we review previous efforts and discuss challenges involved in establishing such a common coordinate framework, the underlying map of tissues and organs. We focus on strategies to handle anatomical variation across individuals and highlight the need for new technologies and analytical methods spanning multiple hierarchical scales of spatial resolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.