Evidence map›Paper›PMID 31834824›Full record

ArticleJournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics2020

Effects of Toll-Like Receptor 4 Inhibition on Transforming Growth Factor-β2 Signaling in the Human Trabecular Meshwork.

Tasneem P Sharma, Stacy Curry, Colleen M McDowell

Open access · greenAbstract read
In one paragraph

Article in Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. The Inducible TGFβ2 Ocular Hypertension Mouse Model.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
  4. Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  5. Review
  6. Article
  7. A20 Attenuates the Fibrotic Response in the Trabecular Meshwork.International journal of molecular sciences · 2022
    Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tasneem P SharmaDepartment of Pharmacology and Neuroscience, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas.
Stacy CurryDepartment of Pharmacology and Neuroscience, North Texas Eye Research Institute, University of North Texas Health Science Center, Fort Worth, Texas.
Colleen M McDowellDepartment of Ophthalmology and Visual Sciences, McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, Wisconsin.
University of North Texas · USUniversity of Wisconsin–Madison · US

Funding

Cross-talk of TGFβ2 and TLR4 in the trabecular meshworkR01EY026529 · NEI · UNIVERSITY OF WISCONSIN-MADISON · PI MCDOWELL, COLLEEN MARY · 2016 to 2022
$2.7M
NEI NIH HHS R01 EY026529
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsCase-Control StudiesCollagen Type IVDisease Models, AnimalDrug Therapy, CombinationExtracellular MatrixFemaleFibronectinsHumansIntraocular PressureMiceMice, Inbred C3HOcular HypertensionOrgan Culture TechniquesSignal TransductionToll-Like Receptor 4Collagen Type IVFibronectinsTLR4 protein, humanToll-Like Receptor 4Transforming Growth Factor beta2glaucomaIOPtrabecular meshwork

Identifiers

PMID31834824
PMCPMC7175615
OpenAlexW2994646162

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.