Evidence map›Paper›PMID 31833218›Full record

ArticlePhysiological reports2019

Slc4a11 disruption causes duct cell loss and impairs NaCl reabsorption in female mouse submandibular glands.

Ning-Yan Yang, Taro Mukaibo, Xin Gao, Ira Kurtz, James E Melvin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Biomolecules · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. The HCells · 2022
    Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Ning-Yan YangSecretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Taro MukaiboSecretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Xin GaoSecretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.
Ira KurtzDepartment of Medicine, Division of Nephrology, David Geffen School of Medicine, and the Brain Research Institute, University of California, Los Angeles, California.
James E MelvinSecretory Mechanisms and Dysfunctions Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland.ORCID 0000-0001-7456-1175
National Institutes of Health · USUniversity of California, Los Angeles · US

Funding

NIDCR DIR Secretory Mechanisms and Dysfunctions SectionZIADE000738 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI MELVIN, JAMES · 2011 to 2019
$14.4M
NIDCR Annual Reports - Veterinary Resources CoreZIGDE000740 · NIDCR · NATIONAL INSTITUTE OF DENTAL & CRANIOFACIAL RESEARCH · PI DAVIDSON, LAUREN · 2012 to 2025
$11.7M
The Biology of NBCe1 in Health and DiseaseR01DK077162 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI IRA KURTZ · 2007 to 2026
$6.7M
NIDCR NIH HHS 1-ZIA-DE000738NIDCR NIH HHS 1-ZIC-DE000740NIDDK NIH HHS DK077162NIDDK NIH HHS R01 DK077162
6 · The paper itself

Abstract

Slc4a11, a member of the Slc4 HCO

Indexed as

Absorption, PhysiologicalProtons4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAmilorideAnimalsAnion Transport ProteinsCells, CulturedCHO CellsCricetinaeCricetulusEpithelial CellsFemaleMaleMiceMice, Inbred C57BLSodium Chloride4,4'-Diisothiocyanostilbene-2,2'-Disulfonic AcidAmilorideAnion Transport ProteinsethylisopropylamilorideProtonsSlc4a11 protein, mouseSodium ChlorideSymportersAcinar cellsductal cellsfluid secretionNaCl reabsorption

Identifiers

PMID31833218
PMCPMC6908739
OpenAlexW2996621162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.