Evidence map›Paper›PMID 31833108›Full record

ArticleAdvanced materials (Deerfield Beach, Fla.)2020

Remote Magnetic Nanoparticle Manipulation Enables the Dynamic Patterning of Cardiac Tissues.

Limor Zwi-Dantsis, Brian Wang, Camille Marijon, Simone Zonetti, Arianna Ferrini, Lucia Massi, Daniel J Stuckey, Cesare M Terracciano, Molly M Stevens

Abstract read
In one paragraph

Article in Advanced materials (Deerfield Beach, Fla.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Cell identity competes with surface tension to determine stromal organization in tumor spheroids beyond the CAF shell paradigm.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  10. Heterogeneous and Composite Bioinks for 3D-Bioprinting of Complex Tissue.Biomedical materials & devices (New York, N.Y.) · 2025
    Review
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  13. Article
  14. Article
  15. Review
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  17. Article
  18. Surface Tension and Neuronal Sorting in Magnetically Engineered Brain-Like Tissue.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Limor Zwi-DantsisDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Prince Consort Road, London, SW7 2AZ, UK.
Brian WangNational Heart & Lung Institute, Imperial College London, The Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
Camille MarijonDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Prince Consort Road, London, SW7 2AZ, UK.
Simone ZonettiDepartment of Electrical and Electronic Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.
Arianna FerriniNational Heart & Lung Institute, Imperial College London, The Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
Lucia MassiDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Prince Consort Road, London, SW7 2AZ, UK.
Daniel J StuckeyCentre for Advanced Biomedical Imaging, University College London, Gower Street, London, WC1E 6BT, UK.
Cesare M TerraccianoNational Heart & Lung Institute, Imperial College London, The Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK.
Molly M StevensDepartment of Materials, Department of Bioengineering, Institute of Biomedical Engineering, Imperial College London, Prince Consort Road, London, SW7 2AZ, UK.ORCID https://orcid.org/0000-0002-7335-266X

Funding

British Heart Foundation FS/10/47/28393British Heart Foundation FS/15/33/31608British Heart Foundation FS/16/76/32409British Heart Foundation RM/17/1/33377British Heart Foundation Centre of Research Excellence RE/13/430184Engineering and Physical Sciences Research Council EP/R004994/1European Union's Horizon 2020 Research and Innovation Programme 659175H2020 Marie Skłodowska-Curie Actions 659175Kusuma Trust UKMedical Research Council MR/R015651/1Medical Research Council MR/R026416/1MRF_ MR/R026416/1Wellcome Trust 098411Wellcome Trust 098411/Z/12/Z
6 · The paper itself

Abstract

The ability to manipulate cellular organization within soft materials has important potential in biomedicine and regenerative medicine; however, it often requires complex fabrication procedures. Here, a simple, cost-effective, and one-step approach that enables the control of cell orientation within 3D collagen hydrogels is developed to dynamically create various tailored microstructures of cardiac tissues. This is achieved by incorporating iron oxide nanoparticles into human cardiomyocytes and applying a short-term external magnetic field to orient the cells along the applied field to impart different shapes without any mechanical support. The patterned constructs are viable and functional, can be detected by T

Indexed as

Biocompatible MaterialsCell LineCollagenEquipment DesignHumansHydrogelsMagnetic FieldsMagnetite NanoparticlesMyocytes, CardiacTissue EngineeringTissue ScaffoldsBiocompatible MaterialsCollagenHydrogelsMagnetite Nanoparticlescardiac tissuescellular organizationhydrogelsmagnetic nanoparticlespatterning

Identifiers

PMID31833108
PMCPMC7015704

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.