Evidence map›Paper›PMID 31833101›Full record

ReviewAdvanced materials (Deerfield Beach, Fla.)2021

Graphene Quantum Dots and Their Applications in Bioimaging, Biosensing, and Therapy.

Seokhwan Chung, Richard A Revia, Miqin Zhang

Open access · greenAbstract readReview
In one paragraph

Review in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 155 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
155citing papers in PubMed, 2 pooled it
24.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

155 citing papers in PubMed, 2 syntheses or guidelines pooled it, 703 citations in OpenAlex.

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  5. 0D/2D Graphene Quantum Dot-MXene Heterostructures: Luminescence, Sensing, and Electrochemical Applications.Luminescence : the journal of biological and chemical luminescence · 2026
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95 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Seokhwan ChungDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Richard A ReviaDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.
Miqin ZhangDepartment of Materials Science and Engineering, University of Washington, Seattle, WA, 98195, USA.ORCID https://orcid.org/0000-0001-8974-1494
University of Washington · US

Funding

Iron oxide nanotheranostics for breast cancerR01EB026890 · NIBIB · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2018 to 2021
$1.9M
Multifunctional nanoparticles to improve treatment of human glioblastomaR01CA161953 · NCI · UNIVERSITY OF WASHINGTON · PI ZHANG, MIQIN · 2013 to 2017
$1.7M
Iron Oxide Nanoparticle-Mediated Radiation Delivery for Glioblastoma TreatmentF31CA232546 · NCI · UNIVERSITY OF WASHINGTON · PI REVIA, RICHARD AARON · 2018 to 2019
$73k
NCI NIH HHS F31 CA232546NCI NIH HHS R01 CA161953NIBIB NIH HHS R01 EB026890NIH HHS F31CA232546NIH HHS NIH/NCI R01CA161953NIH HHS NIH/NIBIB R01EB026890
6 · The paper itself

Abstract

Graphene quantum dots (GQDs) are carbon-based, nanoscale particles that exhibit excellent chemical, physical, and biological properties that allow them to excel in a wide range of applications in nanomedicine. The unique electronic structure of GQDs confers functional attributes onto these nanomaterials such as strong and tunable photoluminescence for use in fluorescence bioimaging and biosensing, a high loading capacity of aromatic compounds for small-molecule drug delivery, and the ability to absorb incident radiation for use in the cancer-killing techniques of photothermal and photodynamic therapy. Recent advances in the development of GQDs as novel, multifunctional biomaterials are presented with a focus on their physicochemical, electronic, magnetic, and biological properties, along with a discussion of technical progress in the synthesis of GQDs. Progress toward the application of GQDs in bioimaging, biosensing, and therapy is reviewed, along with a discussion of the current limitations and future directions of this exciting material.

Indexed as

Biosensing TechniquesGraphiteQuantum DotsAnimalsHumansNeoplasmsOptical ImagingGraphitebioimagingdrug deliverygraphenenanomedicinequantum dots

Identifiers

PMID31833101
PMCPMC7289657
OpenAlexW2995078794

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.