Evidence map›Paper›PMID 31833012›Full record

ArticleJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2020

WATCHMAN implantation in patients with a history of atrial fibrillation and intracranial hemorrhage.

William J Hucker, Joshua A Cohen, M Edip Gurol, E Kevin Heist, Carola Gianni, Jennifer Galvin, Donita Atkins, Sudha Bommana, Luigi Di Biase, Jeremy Ruskin and 5 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. A practical approach to the management of cerebral amyloid angiopathy.International journal of stroke : official journal of the International Stroke Society · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

William J HuckerCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
Joshua A CohenCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
M Edip GurolCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
E Kevin HeistCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
Carola GianniTexas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Jennifer GalvinCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
Donita AtkinsKansas City Heart Rhythm Institute, KS, Overland Park, KS, 66211, USA.
Sudha BommanaKansas City Heart Rhythm Institute, KS, Overland Park, KS, 66211, USA.
Luigi Di BiaseAlbert Einstein College of Medicine at Montefiore Hospital, NY, New York, USA.
Jeremy RuskinCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA.
Sanghamitra MohantyTexas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Rodney HortonTexas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Dhanunjaya LakkireddyKansas City Heart Rhythm Institute, KS, Overland Park, KS, 66211, USA.
Andrea NataleTexas Cardiac Arrhythmia Institute, St. David's Medical Center, Austin, TX, USA.
Moussa MansourCorrigan Minehan Heart Center, Massachusetts General Hospital, 55 Fruit Street GRB 109, Boston, MA, 02114, USA. mmansour@mgh.harvard.edu.
Massachusetts General Hospital · USHeart Rhythm Society · USSt David's Medical Center · USTexas Cardiac Arrhythmia · USChildren's Hospital at Montefiore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUse of oral anticoagulation (OAC) in patients with a history of intracranial hemorrhage (ICH) is often considered high risk as OAC-related ICH is associated with high mortality rates. Left atrial appendage closure with a WATCHMAN device is an alternative management strategy to OAC to decrease thrombotic risk in atrial fibrillation patients; however use of OAC followed by dual antiplatelet therapy (DAPT) or DAPT therapy alone is required for 6 months post-procedurally. In this study, we examined the safety of WATCHMAN implantation followed by 6 months of anti-thrombotic therapy in patients with a history of ICH.

methodsThis is a retrospective analysis of 63 patients with a history of ICH prior to WATCHMAN implantation (Group I) and 95 patients without a history of ICH who underwent WATCHMAN placement (Group II). The primary outcome was death, stroke, or major bleeding within 6 months of WATCHMAN placement.

resultsThe average CHA

conclusionIn a retrospective, multicenter series of patients with a history of ICH prior to WATCHMAN implantation, WATCHMAN placement was performed safely with 6-month outcomes that were similar to patients without a history of ICH, encompassing the time during which a patient with a history of ICH would need antithrombotic therapy to facilitate WATCHMAN placement.

Indexed as

Atrial AppendageAtrial FibrillationStrokeAnticoagulantsHumansIntracranial HemorrhagesRetrospective StudiesTreatment OutcomeAnticoagulantsAtrial fibrillationIntracranial hemorrhageLeft atrial appendage closureWATCHMAN

Identifiers

PMID31833012
OpenAlexW2996244689

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.