Evidence map›Paper›PMID 31832997›Full record

SynthesisNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2020

Personality profile and depression in migraine: a meta-analysis.

Federica Garramone, Chiara Baiano, Antonio Russo, Alfonsina D'Iorio, Gioacchino Tedeschi, Luigi Trojano, Gabriella Santangelo

Abstract readMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Psychological interventions for migraine.Nature reviews. Neurology · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Real-world application of Short Term Psychodynamic Psychotherapy (STPP) as chronic migraine preventive therapy: Profiling responders and predictive factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
    Observational
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Emotional Problems in Pediatric Headache Patients.Current pain and headache reports · 2022
    Review
  16. Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Federica GarramoneDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Chiara BaianoDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Antonio RussoHeadache Center, Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Alfonsina D'IorioDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Gioacchino TedeschiHeadache Center, Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Luigi TrojanoDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy.
Gabriella SantangeloDepartment of Psychology, University of Campania "Luigi Vanvitelli", Caserta, Italy. gabriella.santangelo@unicampania.it.ORCID http://orcid.org/0000-0002-7728-852X
University of Campania "Luigi Vanvitelli" · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the clinical importance of psychological factors in migraine, the relationship between personality traits, depression, and migraine has been poorly investigated.

objectiveTo delineate the personality profile distinctive for migraineurs and to explore the relationship between personality traits and depression in migraineurs compared to non-migraineurs.

methodsA systematic literature search was performed up to March 2019 using PsycInfo (PROQUEST), PubMed and Scopus. Sixteen primary studies met inclusion and exclusion criteria and were included in the meta-analysis.

resultsThe meta-analysis on the personality defined according to Psychobiological model revealed high Harm Avoidance (Hedges'g = 0.31; 95% confidence interval [CI] = 0.01-0.60), Persistence (Hedges'g = 0.37; 95% CI = 0.01to - 0.72) and low self-directedness (Hedges'g = - 0.33; 95% CI = -0.57 to - 0.09) in migraineurs. The meta-analysis on the personality defined according to Three Factor Model revealed high neuroticism (Hedges'g = 0.47; 95% CI = 0.32-0.63) and low extraversion (Hedges'g = - 0.08; 95% CI = - 0.14 to - 0.03) in migraineurs. Meta-regression analysis revealed that neuroticism moderated the relationship between depression and migraine.

conclusionThe findings evidenced that migraine is characterized by specific personality traits. Among them, neuroticism influenced the severity of depression in migraineurs, and, therefore, an early evaluation of the personality traits could allow identifying patients susceptible to develop migraine-associated psychopathological symptoms.

Indexed as

DepressionHumansMigraine DisordersPersonalityDepressionMeta-analysisMigrainePersonality traits

Identifiers

PMID31832997
OpenAlexW2995606251

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.