ArticleCerebellum (London, England)2020
Neuropsychological Profile in Children with Posterior Fossa Tumors with or Without Postoperative Cerebellar Mutism Syndrome (CMS).
Article in Cerebellum (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
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Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 59 citations in OpenAlex.
- Neurological, Neuropsychological, and Social Outcomes in Pediatric Patients Diagnosed With Cerebellar Mutism Syndrome: A Systematic Review.Pediatric blood & cancer · 2025Pooled it
- Genetic susceptibility to cognitive decline following craniospinal irradiation for pediatric central nervous system tumors.Neuro-oncology · 2023Pooled it
- Neurocognitive outcomes in pediatric brain tumors after treatment with proton versus photon radiation: a systematic review and meta-analysis.World journal of pediatrics : WJP · 2023Pooled it
- Language Processing in Posterior Fossa Tumour Patients: Psycholinguistic Insights into the Word-Finding Ability.Cerebellum (London, England) · 2026Article
- Analysis of Presurgical Language in Children with Posterior Fossa Tumours Relative to Postoperative Speech Outcomes: Findings from the European CMS Study.Cerebellum (London, England) · 2026Article
- Altered System-Level Integration Between Working Memory and Gaze Dynamics in Children Treated for Posterior Fossa Tumors.Psychology in Russia : state of the art · 2026Article
- A predictive model for cerebellar mutism syndrome based on lesion map in children with medulloblastoma.European radiology · 2025Article
- Postoperative word-finding difficulties in children with posterior fossa tumours: a crosslinguistic European cohort study.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Review
- Prospective analysis on possible changes of cognitive functions in children on follow-up for brain tumor.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025Article
- Errors in the Spontaneous Language of Survivors of Pediatric Cerebellar Tumors.Cerebellum (London, England) · 2025Article
- MRI identifies disrupted cerebral development in medulloblastoma patients.Brain communications · 2025Article
- Academic readiness among young children treated for brain tumors: a multisite, prospective, longitudinal trial.Journal of the National Cancer Institute · 2024Article
- Oculomotor Impairments in Children After Posterior Fossa Tumors Treatment.Cerebellum (London, England) · 2024Article
- Characterising the Long-Term Language Impairments of Children Following Cerebellar Tumour Surgery by Extracting Psycholinguistic Properties from Spontaneous Language.Cerebellum (London, England) · 2024Article
- Neuroanatomy of cerebellar mutism syndrome: the role of lesion location.Brain communications · 2024Article
- Male Predisposition in Cerebellar Mutism Syndrome: a Cohort Study.Cerebellum (London, England) · 2023Article
- Long-term postoperative quality of life in childhood survivors with cerebellar mutism syndrome.Frontiers in psychology · 2023Article
- Sociocultural variables have a major impact on participation in patients treated for paediatric posterior fossa tumours.Child: care, health and development · 2023Article
- The Cerebellar Mutism Syndrome: Risk Assessment, Prevention and Treatment.Advances and technical standards in neurosurgery · 2023Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar mutism syndrome (CMS) is a common surgical sequela in children following posterior fossa tumor (PFT) resection. Here, we analyze the neuropsychological features associated with PFT in children, focusing particularly on the differential profiles associated with the presence or absence of CMS after surgery. We further examine the effect of post-resection treatments, tumor type, and presence/absence of hydrocephalus on surgical outcome. Thirty-six patients diagnosed with PFT (19 with and 17 without CMS) and 34 age- and gender-matched healthy controls (HCs) were recruited. A comprehensive neuropsychological evaluation was conducted in all patients postoperatively and in HCs, including an assessment of general cognitive ability, motor skills, perception, language, memory, attention, executive functions, and academic competence. CMS was found to be a clinical marker of lower neuropsychological profile scores across all cognitive domains except auditory-verbal processing and visual memory tasks. PFT patients not presenting CMS exhibited milder impairment in intellectual functioning, motor tasks, reasoning, language, verbal learning and recall, attention, cognitive executive functions, and academic competence. High-grade tumors were associated with slower processing speed and verbal delayed recall as well as alterations in selective and sustained attention. Hydrocephalus was detrimental to motor functioning and nonverbal reasoning. Patients who had undergone surgery, chemotherapy, and radiotherapy presented impaired processing speed, verbal learning, and reading. In addition to the deleterious effects of PFT, post-resection PFT treatments have a negative cognitive impact. These undesired consequences and the associated tumor-related damage can be assessed using standardized, long-term neuropsychological evaluation when planning rehabilitation.
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