Evidence map›Paper›PMID 31832875›Full record

ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2020

Multispectral diffusion-weighted MRI of the instrumented cervical spinal cord: a preliminary study of 5 cases.

Kevin M Koch, Sampada Bhave, S Sivaram Kaushik, Andrew S Nencka, Matthew D Budde

Open access · greenAbstract read
In one paragraph

Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Kevin M KochDepartment of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53202, USA. kmkoch@mcw.edu.ORCID 0000-0003-4490-9761
Sampada BhaveDepartment of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53202, USA.
S Sivaram KaushikGE Healthcare, Milwaukee, WI, USA.
Andrew S NenckaDepartment of Radiology, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53202, USA.
Matthew D BuddeDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Medical College of Wisconsin · USWheaton Franciscan Healthcare · US

Funding

Enabling Diffusion-Weighted MRI Near Metallic ImplantsR21EB023415 · NIBIB · MEDICAL COLLEGE OF WISCONSIN · PI KOCH, KEVIN M · 2017 to 2018
$422k
NIBIB NIH HHS R21 EB023415
6 · The paper itself

Abstract

purposeDiffusion-weighted imaging has undergone substantial investigation as a potential tool for advanced assessment of spinal cord health. Unfortunately, commonly encountered surgically implanted spinal hardware has historically disrupted these studies. This preliminary investigation applies the recently developed multispectral diffusion-weighted PROPELLER technique to quantitative assessment of the spinal cord immediately adjacent to metallic spinal fusion instrumentation.

methodsMorphological and diffusion-weighted MRI of the spinal cord was collected from 5 subjects with implanted cervical spinal fusion hardware. Conventional and multispectral diffusion-weighted images were also collected on a normative non-instrumented control cohort and utilized for methodological stability analysis. Variance of the ADC values derived from the normative control group was then analyzed on a subject-by-subject basis and qualitatively correlated with clinical morphological interpretations.

resultsNormative control ADC values within the spinal cord were stable across DWI methods for a b value of 600 s/mm

conclusionsIn the absence of instrumentation, multispectral DWI provides quantitative capabilities that match with those of conventional DWI approaches. In a preliminary instrumented subject analysis, cord ADC values showed both expected and unexpected variations from the normative cohort. These slides can be retrieved under Electronic Supplementary Material.

Indexed as

Cervical CordSpinal Cord DiseasesDiffusion Magnetic Resonance ImagingHumansNeckSpinal CordCervical spineFusionHardwareMRI

Identifiers

PMID31832875
PMCPMC7225051
OpenAlexW2995941650

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.