Evidence map›Paper›PMID 31832823›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Effects of age and gender in patients receiving doses of opioids for breakthrough pain proportional to background opioid doses.

Sebastiano Mercadante, Vincenzo Restivo, Alessandra Casuccio

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Sebastiano MercadanteAnesthesia & Intensive care and Pain relief & Supportive care, La Maddalena Cancer Center, Palermo, Italy. terapiadeldolore@lamaddalenanet.it.
Vincenzo RestivoDepartment of Health Promotion, Mother-Child Care, Internal Medicine and Excellence Specialist Medicine 'G D'Alessandro', University of Palermo, Palermo, Italy.
Alessandra CasuccioDepartment of Health Promotion, Mother-Child Care, Internal Medicine and Excellence Specialist Medicine 'G D'Alessandro', University of Palermo, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo identify the role of age and gender in analgesic and adverse effects after administering fentanyl products for breakthrough pain (BT), given in doses proportional to opioid doses given for background pain.

methodsData from nine studies, in which patients with BP were given fentanyl products in doses proportional to their basal opioid regimen, were analyzed.

resultsA total 462 patients presenting 1905 episodes of BP were included in this analysis. In older patients, the decrease in pain intensity was more pronounced 15 min after administration of a BP medication. No gender differences were found. No significant differences in frequency and intensity of adverse effects for age and gender were found.

conclusionFentanyl products given for BP in doses proportional to background opioid regimen were more effective in older patients without adding risks of adverse effects. Gender did not influence analgesia and adverse effects of fentanyl products.

Indexed as

AgedAge FactorsAnalgesics, OpioidBreakthrough PainFemaleGender IdentityHumansMalePain MeasurementTreatment OutcomeAnalgesics, OpioidAgeBreakthrough painCancer painFentanylGender

Identifiers

PMID31832823

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.