Evidence map›Paper›PMID 31832781›Full record

ArticleJournal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry2020

Mixed ligand complexes of Co(II), Ni(II) and Cu(II) with quercetin and diimine ligands: synthesis, characterization, anti-cancer and anti-oxidant activity.

Hasene Mutlu Gençkal, Merve Erkisa, Pınar Alper, Saliha Sahin, Engin Ulukaya, Ferda Ari

Abstract read
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In one paragraph

Article in Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Concomitant induction of apoptosis and suppression of epithelial-mesenchymal transition (EMT) by a Cu(II)-flavonoid complex in colorectal cancer.Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine · 2026
    Article
  2. Article
  3. Advances in quercetin-based therapeutics for breast cancer: natural, synthetic, and nanotechnology-driven approaches.Medicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Magnetic UiO-66-NHACS omega · 2023
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hasene Mutlu GençkalDepartment of Chemistry, Faculty of Science and Arts, Bursa Uludag University, 16059, Bursa, Turkey.ORCID http://orcid.org/0000-0002-0026-7755
Merve ErkisaDepartment of Biology, Faculty of Science and Arts, Bursa Uludag University, 16059, Bursa, Turkey.ORCID http://orcid.org/0000-0002-3127-742X
Pınar AlperDepartment of Biology, Faculty of Science and Arts, Bursa Uludag University, 16059, Bursa, Turkey.ORCID http://orcid.org/0000-0001-9631-3551
Saliha SahinDepartment of Chemistry, Faculty of Science and Arts, Bursa Uludag University, 16059, Bursa, Turkey.ORCID http://orcid.org/0000-0003-2887-5688
Engin UlukayaDepartment of Clinical Biochemistry, Faculty of Medicine, Istinye University, 34010, Istanbul, Turkey.ORCID http://orcid.org/0000-0003-4875-5472
Ferda AriDepartment of Biology, Faculty of Science and Arts, Bursa Uludag University, 16059, Bursa, Turkey. ferdaoz@uludag.edu.tr.ORCID http://orcid.org/0000-0002-6729-7908

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this work, mixed ligand complexes of Co(II) Ni(II) and Cu(II) were synthesized using quercetin and diimine (1,10-phenanthroline or 2,2'-bipyiridine) ligands. The obtained Ni(II) and Co(II) complexes are new and the Cu(II) complexes are synthesized by different method from the literature. The characterization of complexes was performed by elemental analysis, thermogravimetric analysis, ESI-MS, UV-visible and infrared spectral analyses, magnetic susceptibility and molar conductivity measurements. It was found that quercetin, diimine and metal(II) ion form 1:1:1 complexes. Resulting data supported octahedral geometry for Ni(II) and Co(II) complexes and square pyramidal geometry for Cu(II) complexes. The proposed compositions are [Co(queH-1)Cl(phen)(H

Indexed as

Antineoplastic AgentsAntioxidantsCell Line, TumorCobaltCoordination ComplexesCopperHumansIminesLigandsNickelQuercetinSpectrum AnalysisAntineoplastic AgentsAntioxidantsCobaltCoordination ComplexesCopperIminesLigandsNickelQuercetin1,10-Phenanthroline2,2′-BipyridineAnti-cancer activityAntioxidant activityCytotoxicityFlavonoid complexesQuercetin

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.