Evidence map›Paper›PMID 31832727›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Hypoxia-induced modulation of glucose transporter expression impacts

Hongping Xia, Jianxiang Chen, Hengjun Gao, Shik Nie Kong, Amudha Deivasigamani, Ming Shi, Tian Xie, Kam M Hui

Abstract read
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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 38 citations in OpenAlex.

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  10. [Research Advances in the Roles of High-Altitude Hypoxic Stress in Hepatocellular Carcinoma].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2024
    Review
  11. Article
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  13. Prognostic PET [Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  14. Review
  15. Article
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  17. Exploring the efficacy ofAbdominal radiology (New York) · 2023
    Article
  18. The application ofQuantitative imaging in medicine and surgery · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Hongping XiaDepartment of Pathology, School of Basic Medical Sciences & Sir Run Run Hospital & State Key Laboratory of Reproductive Medicine & Key Laboratory of Antibody Technique of National Health Commission, Nanjing Medical University, Nanjing, 211166, China. xiahongping@njmu.edu.cn.ORCID 0000-0002-5663-8092
Jianxiang ChenHolistic Integrative Pharmacy Institutes, School of Medicine & Key Laboratory of Elemene Anti-cancer Medicine of Zhejiang Province & Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, Hangzhou Normal University, Hangzhou, 311100, China.
Hengjun GaoShandong Provincial Hospital Affiliated to Shandong University, Jinan, 250021, China.
Shik Nie KongLaboratory of Cancer Genomics, National University of Cancer Centre, 11 Hospital Drive, Singapore, 169610, Singapore.
Amudha DeivasigamaniLaboratory of Cancer Genomics, National University of Cancer Centre, 11 Hospital Drive, Singapore, 169610, Singapore.
Ming ShiDepartment of Hepatobiliary Oncology, Cancer Center, Sun Yat-sen University, Guangzhou, 510060, China.
Tian XieHolistic Integrative Pharmacy Institutes, School of Medicine & Key Laboratory of Elemene Anti-cancer Medicine of Zhejiang Province & Engineering Laboratory of Development and Application of Traditional Chinese Medicine from Zhejiang Province, Hangzhou Normal University, Hangzhou, 311100, China.
Kam M HuiDepartment of Pathology, School of Basic Medical Sciences & Sir Run Run Hospital & State Key Laboratory of Reproductive Medicine & Key Laboratory of Antibody Technique of National Health Commission, Nanjing Medical University, Nanjing, 211166, China. cmrhkm@nccs.com.sg.
Hangzhou Normal University · CNNational Cancer Centre Singapore · SGShandong University · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the molecular mechanisms underlying the variable standard uptake value (SUV) of MATERIALS AND

methodsSixteen HCC specimens obtained from patients who underwent pre-treatment staging with

resultsGlucose transporters are differentially expressed between samples from HCC patients with high and low SUV

conclusionOver-expression of GLUT1 and GLUT3 significantly increase glucose uptake in HCC cells. Hypoxia-induced glucose transporters expression may therefore be a contributing variable in

Indexed as

Carcinoma, HepatocellularHypoxiaLiver NeoplasmsFluorodeoxyglucose F18Glucose Transporter Type 1Glucose Transporter Type 3HumansNeoplasm Recurrence, LocalPositron-Emission TomographyPositron Emission Tomography Computed TomographyFluorodeoxyglucose F18Glucose Transporter Type 1Glucose Transporter Type 3SLC2A1 protein, humanSLC2A3 protein, human18F-fluorodeoxyglucose positron emission tomography-computed tomographyGlucose transporterHepatocellular carcinomaHypoxiaStandard uptake value

Identifiers

PMID31832727
OpenAlexW2996681413

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.