Evidence map›Paper›PMID 31832694›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2020

Risk for hip fracture before and after total knee replacement in Sweden.

C H Vala, J Kärrholm, J A Kanis, H Johansson, S Sten, V Sundh, M Karlsson, M Lorentzon, D Mellström

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04796519 (A Comparison of Balance and Fall Risk in Patients With Unilateral and Bilateral Total Knee Arthroplasty), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04796519 nacompletednot on this map

A Comparison of Balance and Fall Risk in Patients With Unilateral and Bilateral Total Knee Arthroplasty

TypeinterventionalSponsorPamukkale UniversityRan2019 to 2020Enrolled45ConditionsKnee ArthropathyArmsTotal knee arthroplasty
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Comorbid Factors and Selection for Same-Day Total Joint Arthroplasty.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2024
    Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

C H ValaGeriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden. cecilie.hongslo.vala@gu.se.ORCID http://orcid.org/0000-0001-8932-9686
J KärrholmDepartment of Orthopedic Surgery, Sahlgrenska Academy, University of Gothenburg, 431 80, Mölndal, Sweden.
J A KanisCentre for Metabolic Bone Disease, Medical School, University of Sheffield, S10 2RX, Sheffield, UK.
H JohanssonGeriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden.
S StenDepartment of Archaeology and Ancient History, Uppsala University- Campus Gotland, 621 57, Visby, Sweden.
V SundhGeriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden.
M KarlssonDepartment of Orthopedics and Clinical Sciences, Lund University, Skåne University Hospital, 205 02, Malmö, Sweden.
M LorentzonGeriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden.
D MellströmGeriatric Medicine, Department of Internal Medicine and Clinical Nutrition, Sahlgrenska Academy, University of Gothenburg, 413 45, Göteborg, Sweden.
Sahlgrenska University Hospital · SEUniversity of Gothenburg · SEAustralian Catholic University · AULund University · SEUppsala University · SE

Funding

ALF from the Swedish government ALFGBG437971ALF from the Swedish government ALFGBG722321Vetenskapsrådet 2017-02229
6 · The paper itself

Abstract

We studied the risk for hip fracture before and after total knee replacement (TKR) in the entire population in Sweden. Women and men had a low risk for hip fracture before TKR but an increased risk the first year after TKR. PURPOSE: It is known that osteoarthritis is associated with high bone mass. We therefore studied the risk of hip fracture before and after total knee replacement (TKR), risk of different hip fracture types, and risk subdivided in genders and age groups.

methodsWe followed the total Swedish population born between 1902 and 1952 (n = 4,258,934) during the period 1987-2002 and identified all patients with TKR due to primary OA (n = 39,291), and all patients with hip fracture (n = 195,860) in the Swedish National Inpatient Register. The risk time analyses were based on Poisson regression models.

resultsThe hazard ratio (HR) for hip fracture the last year before TKR was 0.86 (95% CI 0.74 to 1.00) and the first year after 1.26 (95% CI 1.11 to 1.42) compared to individuals without TKR. The HR for femoral neck fracture 0-10 years after TKR was 0.95 (95% CI 0.89 to 1.01) and for trochanteric fracture was 1.13 (95% CI 1.06 to 1.21). The HR for hip fracture in the age group 50-74 was 1.28 (95% CI 1.14 to 1.43) and in the age group 75-90 years was 0.99 (95% CI 0.94 to 1.04) 0-10 years after TKR, compared to individuals without TKR.

conclusionIndividuals had a low risk for hip fracture before TKR but an increased risk the first year after TKR. The risk in individuals below age 75 years and for trochanteric fractures was increased after TKR. Possible explanations include changed knee kinematics after a TKR, physical activity level, fall risk, and other unknown factors.

Indexed as

Arthroplasty, Replacement, HipArthroplasty, Replacement, KneeHip FracturesOsteoarthritis, KneePelvic BonesAgedAged, 80 and overFemaleHumansMaleRisk FactorsSwedenFemur neck fractureHip fractureOsteoarthritisTotal knee replacementTrochanteric fracture

Identifiers

PMID31832694
PMCPMC7170830
OpenAlexW2996451015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.