ArticleDatabase : the journal of biological databases and curation2019
AcetoBase: a functional gene repository and database for formyltetrahydrofolate synthetase sequences.
Article in Database : the journal of biological databases and curation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Salinity Impacts the FunctionalMicroorganisms · 2023Article
- Co-substrate composition is critical for enrichment of functional key species and for process efficiency during biogas production from cattle manure.Microbial biotechnology · 2023Article
- Interpreting tree ensemble machine learning models with endoR.PLoS computational biology · 2022Article
- AcetoBase Version 2: a database update and re-analysis of formyltetrahydrofolate synthetase amplicon sequencing data from anaerobic digesters.Database : the journal of biological databases and curation · 2022Article
- Syntrophic propionate-oxidizing bacteria in methanogenic systems.FEMS microbiology reviews · 2022Review
- Article
- Microbiological Surveillance of Biogas Plants: Targeting Acetogenic Community.Frontiers in microbiology · 2021Article
- nZVI Impacts Substrate Conversion and Microbiome Composition in Chain Elongation From D- and L-Lactate Substrates.Frontiers in bioengineering and biotechnology · 2021Article
- High-Throughput Sequencing and Unsupervised Analysis of Formyltetrahydrofolate Synthetase (FTHFS) Gene Amplicons to Estimate Acetogenic Community Structure.Frontiers in microbiology · 2020Article
Corrections and comments
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Authors and funding
4 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Acetogenic bacteria are imperative to environmental carbon cycling and diverse biotechnological applications, but their extensive physiological and taxonomical diversity is an impediment to systematic taxonomic studies. Acetogens are chemolithoautotrophic bacteria that perform reductive carbon fixation under anaerobic conditions through the Wood-Ljungdahl pathway (WLP)/acetyl-coenzyme A pathway. The gene-encoding formyltetrahydrofolate synthetase (FTHFS), a key enzyme of this pathway, is highly conserved and can be used as a molecular marker to probe acetogenic communities. However, there is a lack of systematic collection of FTHFS sequence data at nucleotide and protein levels. In an attempt to streamline investigations on acetogens, we developed AcetoBase - a repository and database for systematically collecting and organizing information related to FTHFS sequences. AcetoBase also provides an opportunity to submit data and obtain accession numbers, perform homology searches for sequence identification and access a customized blast database of submitted sequences. AcetoBase provides the prospect to identify potential acetogenic bacteria, based on metadata information related to genome content and the WLP, supplemented with FTHFS sequence accessions, and can be an important tool in the study of acetogenic communities. AcetoBase can be publicly accessed at https://acetobase.molbio.slu.se.
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