Evidence map›Paper›PMID 31832580›Full record

ArticleBJS open2019

Video-assisted thoracoscopic surgery for ectopic mediastinal parathyroid adenoma.

K E Isaacs, S Belete, B J Miller, A N Di Marco, S Kirby, T Barwick, N S Tolley, J R Anderson, F F Palazzo

Open access · goldAbstract read
In one paragraph

Article in BJS open, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Surgical Management of Mediastinal Ectopic Parathyroids.Journal of personalized medicine · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

K E IsaacsDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.ORCID 0000-0002-1683-2915
S BeleteDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.ORCID 0000-0003-4073-8547
B J MillerDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.ORCID 0000-0001-5368-2605
A N Di MarcoDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.ORCID 0000-0002-0079-1194
S KirbyDepartment of Radiology Imperial College Healthcare NHS Trust London UK.
T BarwickDepartment of Anaesthesia Imperial College Healthcare NHS Trust London UK.
N S TolleyDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.
J R AndersonDepartment of Cardiothoracic Surgery, Hammersmith Hospital Imperial College Healthcare NHS Trust London UK.
F F PalazzoDepartment of Endocrine Surgery Imperial College Healthcare NHS Trust London UK.
Imperial College Healthcare NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Primary hyperparathyroidism (PHPT), caused by an ectopic mediastinal parathyroid adenoma, is uncommon. In the past, when the adenoma was not accessible from the neck, median sternotomy was advocated for safe and successful parathyroidectomy. Video-assisted thoracoscopic surgical (VATS) parathyroidectomy represents a modern alternative approach to this problem. Methods: Information on patients undergoing VATS was obtained from a specific database, including clinical presentation, biochemistry, preoperative imaging, surgical approach and patient outcomes. A comprehensive literature review was undertaken to draw comparisons with other publications. Results: Over a 2-year period, nine patients underwent VATS parathyroidectomy for sporadic PHPT. Five patients had persistent PHPT following previous unsuccessful parathyroidectomy via cervicotomy, and four had had no previous parathyroid surgery. The median duration of surgery was 90 (range 60-160) min. Eight patients were cured biochemically, with no major complications. One patient required conversion to a median sternotomy for removal of a thymoma that had resulted in false-positive preoperative imaging. Conclusion: With appropriate preoperative imaging, multidisciplinary input and expertise, VATS parathyroidectomy is an effective, safe and well tolerated approach to ectopic mediastinal parathyroid adenoma.

Indexed as

Parathyroid GlandsAdenomaAdultChoristomaConversion to Open SurgeryFemaleHumansHyperparathyroidism, PrimaryMaleMediastinal NeoplasmsMediastinumMiddle AgedOperative TimeParathyroidectomyProspective StudiesSternotomy

Identifiers

PMID31832580
PMCPMC6887896
OpenAlexW2969311169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.