Evidence map›Paper›PMID 31832548›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2019

A pilot study to examine the association between human gut microbiota and the host's central obesity.

Seok Hwee Koo, Collins Wenhan Chu, Joan Joo Ching Khoo, Magdalin Cheong, Gaik Hong Soon, Eliza Xin Pei Ho, Ngai Moh Law, Paola Florez De Sessions, Kwong Ming Fock, Tiing Leong Ang and 2 more

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Seok Hwee KooClinical Trials and Research Unit Changi General Hospital Singapore Singapore.ORCID https://orcid.org/0000-0003-4556-2624
Collins Wenhan ChuGERMS Platform, Genome Institute of Singapore Agency for Science, Technology and Research Singapore Singapore.
Joan Joo Ching KhooDepartment of Endocrinology Changi General Hospital Singapore Singapore.
Magdalin CheongDepartment of Dietetic and Food Services Changi General Hospital Singapore Singapore.
Gaik Hong SoonClinical Trials and Research Unit Changi General Hospital Singapore Singapore.
Eliza Xin Pei HoGERMS Platform, Genome Institute of Singapore Agency for Science, Technology and Research Singapore Singapore.
Ngai Moh LawDepartment of Gastroenterology and Hepatology Changi General Hospital Singapore Singapore.
Paola Florez De SessionsGERMS Platform, Genome Institute of Singapore Agency for Science, Technology and Research Singapore Singapore.
Kwong Ming FockDepartment of Gastroenterology and Hepatology Changi General Hospital Singapore Singapore.
Tiing Leong AngDepartment of Gastroenterology and Hepatology Changi General Hospital Singapore Singapore.
Edmund Jon Deoon LeeClinical Trials and Research Unit Changi General Hospital Singapore Singapore.
John Chen HsiangDepartment of Gastroenterology and Hepatology Changi General Hospital Singapore Singapore.
Changi General Hospital · SGAgency for Science, Technology and Research · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimPerturbance in the composition of human gut microbiota has been associated with metabolic disorders such as obesity, diabetes mellitus, and insulin resistance. The objectives of this study are to examine the effects of ethnicity, central obesity, and recorded dietary components on potentially influencing the human gut microbiome. We hypothesize that these factors have an influence on the composition of the gut microbiome.

methodsSubjects of Chinese (

resultsThere were no significant differences in Shannon alpha diversity for ethnicity and central obesity and no associations between levels of inflammatory cytokines and obesity. The relative abundances of

conclusionThe study demonstrated that there were differences in the gut microbiome in obese individuals. Certain bacterial taxa were present in lower abundance in the group with central obesity. Fiber and fat/saturated fat diets were not the key determinants of central obesity.

Indexed as

continental population groupsdietmetabolic syndromemicrobiotaobesity

Identifiers

PMID31832548
PMCPMC6891071
OpenAlexW2937916918

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.