Evidence map›Paper›PMID 31832438›Full record

ArticleReports of biochemistry & molecular biology2019

Association of Endonuclease G Gene Variants with Cardiovascular Disease Risk Factors.

Negar Etehad Roodi, Nushin Karkuki Osguei, Mahdy Hasanzadeh Daloee, Alireza Pasdar, Majid Ghayour-Mobarhan, Gordon Ferns, Ali Samadi Kuchaksaraei

Open access · greenAbstract read
In one paragraph

Article in Reports of biochemistry & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Negar Etehad RoodiCellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran.
Nushin Karkuki OsgueiEposcience Millennium Institute, Tehran, Iran.
Mahdy Hasanzadeh DaloeeCardiovascular Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Alireza PasdarMolecular Medicine Group, Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid Ghayour-MobarhanMetabolic Syndrome Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Gordon FernsBrighton & Sussex Medical School, Division of Medical Education, Falmer, Brighton, Sussex BN1 9PH, UK.
Ali Samadi KuchaksaraeiCellular and Molecular Research Centre, Iran University of Medical Science, Tehran, Iran.
Mashhad University of Medical Sciences · IRBrighton and Sussex Medical School · GBGhaem Hospital · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) is a leading cause of death, supporting the need for the identification of novel biomarkers as risk stratification factors. Endonuclease G (ENDOG) has recently been suggested to be a novel determinant of cardiac hypertrophy and mitochondrial function, and plays an important role in apoptosis processes involved in cardiac myocyte death. The aim of current study was to explore the association of two genetic variants in ENDOG gene (

methodsSubjects included 663 patients with CVD and 282 healthy individuals recruited as part of the Mashhad Stroke and Heart Atherosclerotic Disorders Cohort Study. The

results

conclusionOur findings indicated an association between an

Indexed as

Cardiac Vascular DiseasesEndonuclease GPolymorphism

Identifiers

PMID31832438
PMCPMC6844608
OpenAlexW2973701487

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.