ArticleReports of biochemistry & molecular biology2019
Estimation of Salivary sCD14 in Children with Early Childhood Caries in Association with Pneumonia.
Article in Reports of biochemistry & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
4 citing papers in PubMed, 11 citations in OpenAlex.
- Article
- sCD14 Level in Saliva of Children and Adolescents with and without Dental Caries, a Hurdle Model.Children (Basel, Switzerland) · 2021Article
- Serum and salivary immunoglobulin G4 levels in children with autism spectrum disorder from south India: a case-control study.American journal of clinical and experimental immunology · 2021Article
- Serum Ischemia-Modified Albumin, Fibrinogen, High Sensitivity C- Reactive Proteins in Type-2 Diabetes Mellitus without Hypertension and Diabetes Mellitus with Hypertension: A Case-Control Study.Reports of biochemistry & molecular biology · 2020Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDental caries is a chronic disease among children and pneumonia is often seen in young children. Soluble CD14 (sCD14) protein is released by monocytes and changes in periodontal infection. The study aimed to estimate the level of salivary sCD14 in children with early childhood caries in association with pneumonia.
methodsThis case-control study was conducted on 52 children aged between 2 to 5 years. A total of 17 children who were caries free, with no past systemic illness; 17 children with dental caries with no history of systemic illness or dental treatment for caries, and 18 children with caries and pneumonia were included in the control and test groups respectively. Unstimulated saliva of all children was collected. All samples were tested using a commercial available sCD14 ELISA kit.
resultsThe sCD14 level was elevated in all three groups. One-way ANOVA was used to compare the mean level of sCD14 values between the groups. Control group had the highest mean sCD14 values (15070.99 ± 4296.44), followed by the caries group (13629.83 ± 5603.76) and pneumonia group (8566.86 ± 4778.81). There is a significant difference between the groups with p=0.001.
conclusionBased on the results of the study, it can be concluded that sCD14 can be used as an indicator of the healthy functioning of the oral cavity.
Indexed as
Identifiers
31832436PMC6844620W2981189961What OpenQuestion holds
Registered trials
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