ArticleReports of biochemistry & molecular biology2019
The Role of Interleukin-4 and 13 Gene Polymorphisms in Allergic Rhinitis: A Case Control Study.
Article in Reports of biochemistry & molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Polymorphisms and AR: A Systematic Review and Meta-Analyses.Frontiers in genetics · 2022Pooled it
- IL-4 rs2243250 polymorphism associated with susceptibility to allergic rhinitis: a meta-analysis.Bioscience reports · 2021Pooled it
- Impact of antigen loading in tolerogenic nanoparticles to mitigate Th2-mediated allergic lung inflammation.Drug delivery and translational research · 2024Article
- TGF-β, IL-1β, IL-6 levels and TGF-β/Smad pathway reactivity regulate the link between allergic diseases, cancer risk, and metabolic dysregulations.Frontiers in immunology · 2024Article
- Association of Rs7217186 Polymorphism of Arachidonic Acid 15-Lipoxygenase (ALOX15) Gene with Susceptibility to Allergic Rhinitis.Reports of biochemistry & molecular biology · 2023Article
- Pathogenesis of allergic diseases and implications for therapeutic interventions.Signal transduction and targeted therapy · 2023Review
- Exploring the latest understanding on the role of immune mediators, genetic and environmental factors in pathogenesis of allergic rhinitis: a systematic review.Frontiers in allergy · 2023Review
- Association between IL1RL1 gene polymorphisms and allergic rhinitis risk in the Chinese Han population.Journal of clinical laboratory analysis · 2022Article
- Correlation BetweenReports of biochemistry & molecular biology · 2022Article
- Effects of rosmarinic acid on the inflammatory response in allergic rhinitis rat models after PM2.5 exposure.Journal of clinical laboratory analysis · 2022Article
- Genetic Variations in Nucleotide Excision Repair Pathway Genes and Risk of Allergic Rhinitis.Mediators of inflammation · 2022Article
- Macrophage Receptor With Collagenous Structure Polymorphism and Recurrent Respiratory Infections and Wheezing During Infancy: A 5-Years Follow-Up Study.Frontiers in pediatrics · 2021Article
- Retinoic Acid Correlates with Reduced Serum IL-10 And TGF-β in Allergic Rhinitis.Reports of biochemistry & molecular biology · 2021Article
- Article
Corrections and comments
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Authors and funding
10 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAllergic Rhinitis (AR) is an IgE-mediated inflammatory disorder with high morbidity rates. The eitiology of this disease is understood to occur from a complex interaction between genetic and environmental factors. T helper type 2 cells have been shown to have a crucial role in atopic disease due to their production of the cytokines, intelukin
methodsA case-control study was designed to investigate the relationship between the two SNPs rs2243250 and rs20541 with the incidence of AR. The SNPs were examined in patients with AR and healthy controls (86 patients and 86 controls). Blood samples were collected and DNA was extracted to evaluate the SNPs by RFLP-PCR.
resultsRecessive analysis model of the
conclusionOur findings suggest that the
Indexed as
Identifiers
31832433PMC6844616W2975003140What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.