ArticleERJ open research2019
Prevalence of comorbidities and impact on pulmonary rehabilitation outcomes.
Article in ERJ open research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Clinical Outcomes Following Exercise Rehabilitation in People with Multimorbidity: A Systematic Review.Journal of rehabilitation medicine · 2023Pooled it
- Exploring the prevalence and impact of hip and knee pain in pulmonary rehabilitation: a propensity-matched cohort study.Respiratory research · 2022Trial
- Real-World Effectiveness and Safety of Extrafine Triple Therapy in COPD Patients with Comorbid and Cardiovascular Conditions.International journal of chronic obstructive pulmonary disease · 2026Article
- Patient Characteristics and Outcomes by Sex and Smoking Status in Pulmonary and Cardiac Rehabilitation.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Article
- Article
- 'Teach me how to look after myself': What people with bronchiectasis want from education in a pulmonary rehabilitation setting.The clinical respiratory journal · 2023Article
- Impact of Cardiovascular and Metabolic Comorbidities on Long-term Outcomes of Home-based Pulmonary Rehabilitation in COPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Comorbidity burden and survival in patients with idiopathic pulmonary fibrosis: the EMPIRE registry study.Respiratory research · 2022Article
- The Importance of Appropriate Diagnosis in the Practical Management of Chronic Obstructive Pulmonary Disease.Diagnostics (Basel, Switzerland) · 2021Review
- Current developments and future directions in COPD.European respiratory review : an official journal of the European Respiratory Society · 2020Article
- A cluster-based analysis evaluating the impact of comorbidities in fibrotic interstitial lung disease.Respiratory research · 2020Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe presence of comorbid conditions could impact performance in pulmonary rehabilitation (PR) programmes. We aimed to compare the comorbidity prevalence among those with chronic obstructive pulmonary disease (COPD) and interstitial lung disease (ILD) and evaluate the impact on PR response.
methodsWe performed a retrospective cohort study, recording comorbidities for all patients with COPD or ILD referred to PR. Participants were classified as responders to PR if they met the minimal important difference for exercise capacity and health-related quality of life (HRQoL). The prevalence of comorbidities and impact on PR outcomes were compared by lung disease and by sex using a univariate analysis and multivariate logistic regression.
resultsThe mean number of comorbidities was similar among those with COPD (3.3±2.1, n=242) and ILD (3.2±1.9, n=66) (p>0.05). Females had a higher number of comorbidities than males in both COPD (p=0.001) and ILD (p=0.017) populations. Circulatory (64%) and endocrine/metabolic (45%) conditions were most common in COPD. In ILD, digestive (55%) and circulatory (53%) comorbidities were most prevalent. In people with ILD, those over 65 years, with musculoskeletal/connective tissue disease or circulatory disease were less likely to obtain meaningful improvements in exercise capacity. There was no impact of comorbidities on exercise capacity in COPD or on HRQoL in ILD.
conclusionsThe majority of patients with COPD or ILD enrolled in PR programmes have multiple comorbidities that may affect improvements in exercise capacity. PR programmes may be less effective for older adults with ILD and comorbid circulatory or musculoskeletal disease.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.