Evidence map›Paper›PMID 31832350›Full record

ArticleAnnals of cardiothoracic surgery2019

Management and outcomes of left ventricular assist device-associated endocarditis: a systematic review.

Sinal Patel, Syed Saif Abbas Rizvi, Jae Hwan Choi, Dylan P Horan, Matthew P Weber, Elizabeth J Maynes, Jessica G Y Luc, Nana Aburjania, John W Entwistle, Rohinton J Morris and 2 more

Open access · diamondAbstract read
In one paragraph

Article in Annals of cardiothoracic surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. ENDOCOR: a nationwide consortium of endocarditis teams-initiating a registry for infective endocarditis within the Netherlands Heart Registration.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025
    Article
  3. Article
  4. Infections in Patients with Mechanical Circulatory Support.Infectious disease clinics of North America · 2024
    Review
  5. Article
  6. Article
  7. Contemporary Management Strategies in VAD Infection.Current heart failure reports · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Sinal PatelDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Syed Saif Abbas RizviDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Jae Hwan ChoiDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Dylan P HoranDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Matthew P WeberDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Elizabeth J MaynesDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Jessica G Y LucDivision of Cardiovascular Surgery, Department of Surgery, University of British Columbia, Vancouver, British Columbia, Canada.
Nana AburjaniaDivision of Infectious Diseases, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
John W EntwistleDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Rohinton J MorrisDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Howard T MasseyDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Vakhtang TchantchaleishviliDivision of Cardiac Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Thomas Jefferson University · USUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft ventricular assist device (LVAD)-associated endocarditis remains poorly studied, especially in newer continuous-flow LVADs (CF-LVADs). The aim of this review was to assess outcomes of patients with LVAD-associated endocarditis, as stratified by CF-LVAD and pulsatile LVAD (P-LVAD) use as well as by different interventions and pathogen types.

methodsAn electronic search was performed to identify studies in the English literature on LVAD-associated endocarditis.

resultsOverall, 16 articles with 26 patients were included; seven had CF-LVADs and 19 had P-LVADs; time to development of endocarditis was 91 days (152

conclusionsCompared to patients with P-LVADs, CF-LVAD patients appeared to be resistant to early development of LVAD-associated endocarditis. There was a trend towards high survival observed amongst patients who underwent additional surgical intervention as compared to those treated with antibiotics alone, with no difference amongst surgical device exchange as compared to heart transplantation. Advantages of additional surgical intervention

Indexed as

endocarditisinfectionLeft ventricular assist device (LVAD)

Identifiers

PMID31832350
PMCPMC6892731
OpenAlexW2942963139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.