Evidence map›Paper›PMID 31832252›Full record

SynthesisWestern Pacific surveillance and response journal : WPSAR2018

Influenza-associated paediatric respiratory hospitalizations in China, 1996-2012: a systematic analysis.

Mei Shang, Kathryn E Lafond, Jeffrey McFarland, Suizan Zhou, John Klena, Marc-Alain Widdowson

Abstract readSystematic Review
In one paragraph

Synthesis in Western Pacific surveillance and response journal : WPSAR, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mei ShangChina-US Collaborative Program on Emerging and Reemerging Infectious Diseases, Centers for Disease Control and Prevention, Beijing, China.
Kathryn E LafondInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Jeffrey McFarlandChina-US Collaborative Program on Emerging and Reemerging Infectious Diseases, Centers for Disease Control and Prevention, Beijing, China.
Suizan ZhouChina-US Collaborative Program on Emerging and Reemerging Infectious Diseases, Centers for Disease Control and Prevention, Beijing, China.
John KlenaChina-US Collaborative Program on Emerging and Reemerging Infectious Diseases, Centers for Disease Control and Prevention, Beijing, China.
Marc-Alain WiddowsonInfluenza Division, Centers for Disease Control and Prevention, Atlanta, GA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe World Health Organization recommends that children aged ≥ 6 months be vaccinated against influenza. Influenza vaccination policies depend on the evidence of the burden of influenza, yet few national data on influenza-associated severe outcomes among children exist in China.

methodsWe conducted a systematic review of articles published from 1996 to 2012 on laboratory-confirmed, influenza-associated paediatric respiratory hospitalizations in China. We extracted data and stratified the percentage of samples testing positive for influenza by age group (< 2, < 5 and < 18 years old); case definition; test methods; and geographic location. The pooled percentage of samples testing positive for influenza was estimated with a random effects regression model.

resultsInfluenza was associated with 8.8% of respiratory hospitalizations among children aged < 18 years, ranging from 7.0% (95% confidence interval: 4.2-9.8%) in children aged < 2 years to 8.9% (95% confidence interval: 6.8-11%) in children aged < 5 years. The percentage of samples testing positive for influenza was consistently higher among studies with data from children aged < 5 years and < 18 years than those restricted only to children aged < 2 years; the percentages were higher in Northern China than Southern China. DISCUSSION: Influenza is an important cause of paediatric respiratory hospitalizations in China. Influenza vaccination of school-aged children could prevent substantial influenza-associated illness, including hospitalizations, in China.

Indexed as

AdolescentAge DistributionChildChild, PreschoolChinaClinical Laboratory TechniquesFemaleHospitalizationHumansInfantInfant, NewbornInfluenza, HumanMaleOrthomyxoviridae

Identifiers

PMID31832252
PMCPMC6902651

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.