ArticleTherapeutic advances in endocrinology and metabolism2019
Evaluation of urinary biomarkers for prediction of diabetic kidney disease: a propensity score matching analysis.
Article in Therapeutic advances in endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Biomarkers in Diabetic Kidney Disease: Early Detection, Prognostic Assessment, and Integration with Multi-Omics Signatures.Life (Basel, Switzerland) · 2026Review
- Real-world effectiveness and safety of finerenone in diabetic kidney disease with preserved eGFR: a retrospective study in China.BMC nephrology · 2026Article
- Modulation of PKCα/ETS1 by klotho restores CYB5R4-dependent mitochondrial function in proximal tubular epithelial cells to attenuate the progression of diabetic kidney disease.Cardiovascular diabetology · 2026Article
- Urinary biomarkers of diabetic kidney disease.World journal of diabetes · 2026Review
- Identifying Diabetic Kidney Disease in Type 2 Diabetes Patients Using Explainable Machine Learning: A Case-Control Study.Journal of diabetes research · 2026Article
- Association Between Cesarean Scar and Pelvic Floor Muscle Tone at 6-8 Weeks Postpartum.International urogynecology journal · 2025Observational
- Application of biomarkers in the diagnosis of kidney disease.Frontiers in medicine · 2025Review
- Urinary Immunoglobulin G Is a Novel Biomarker for Atherosclerotic Burden in Mild Acute Ischemic Stroke Patients.Journal of atherosclerosis and thrombosis · 2024Article
- Simultaneous detection of multiple urinary biomarkers in patients with early-stage diabetic kidney disease using Luminex liquid suspension chip technology.Frontiers in endocrinology · 2024Article
- Association between functional constipation and vaginal wind in women at 6 weeks postpartum.International urogynecology journal · 2023Article
- Urine Immunoglobin G Greater Than 2.45 mg/L Has a Correlation with the Onset and Progression of Diabetic Kidney Disease: A Retrospective Cohort Study.Journal of personalized medicine · 2023Article
- Identification of a novel immune landscape signature as effective diagnostic markers related to immune cell infiltration in diabetic nephropathy.Frontiers in immunology · 2023Article
- Diagnostic value of α1-MG and URBP in early diabetic renal impairment.Frontiers in physiology · 2023Article
- Review of potential biomarkers of inflammation and kidney injury in diabetic kidney disease.Diabetes/metabolism research and reviews · 2022Review
- Urinary RBP as an Independent Predictor of Renal Outcome in Diabetic Nephropathy.Disease markers · 2022Article
- Evaluation of Urinary Biomarkers of Proximal Tubular Injury, Inflammation, and Fibrosis in Patients With Albuminuric and Nonalbuminuric Diabetic Kidney Disease.Kidney international reports · 2021Article
- Distribution of urinary N-acetyl-beta-D-glucosaminidase and the establishment of reference intervals in healthy adults.Journal of clinical laboratory analysis · 2021Article
- Hyperinsulinemia contributes to impaired-glucose-tolerance-induced renal injuryTherapeutic advances in chronic disease · 2020Article
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to evaluate the diagnostic value of six urinary biomarkers for prediction of diabetic kidney disease (DKD).
methodsThe cross-sectional study recruited 1053 hospitalized patients with type 2 diabetes mellitus (T2DM), who were categorized into the diabetes mellitus (DM) with normoalbuminuria (NA) group (
resultsPatients with DKD had higher levels of all six urinary biomarkers. All indicators demonstrated significantly increased risk of DKD, except for GAL and β2MG. Single RBP yielded the greatest area under the curve (AUC) value of 0.920 compared with the other five markers, followed by TF (0.867) and IgG (0.867). However, GAL, NAG, and β2MG were shown to have a weak prognostic ability. The diagnostic values of the different combinations were not superior to the single RBP.
conclusionsRBP, TF, and IgG could be used as reliable or good predictors of DKD. The combined use of these biomarkers did not improve DKD detection.
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