Evidence map›Paper›PMID 31832112›Full record

ReviewThe EPMA journal2019

Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles.

Shehua Qian, Olga Golubnitschaja, Xianquan Zhan

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The EPMA journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 4 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 4 syntheses or guidelines pooled it, 199 citations in OpenAlex.

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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Shehua Qian1Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008 Hunan People's Republic of China.
Olga Golubnitschaja4Radiological Clinic, UKB, Excellence Rheinische Friedrich-Wilhelms-University of Bonn, Sigmund-Freud-Str 25, 53105 Bonn, Germany.
Xianquan Zhan1Key Laboratory of Cancer Proteomics of Chinese Ministry of Health, Xiangya Hospital, Central South University, 87 Xiangya Road, Changsha, 410008 Hunan People's Republic of China.ORCID 0000-0002-4984-3549
Central South University · CNUniversity of Bonn · DE

Funding

Prefrontal-Accumbens Glutamate and Ethanol Escalation in Adolescent and Adult C57R01AA020610 · NIAAA · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI MELENDEZ, ROBERTO I · 2014 to 2018
$1.8M
NIAAA NIH HHS R01 AA020610
6 · The paper itself

Abstract

A strong relationship exists between tumor and inflammation, which is the hot point in cancer research. Inflammation can promote the occurrence and development of cancer by promoting blood vessel growth, cancer cell proliferation, and tumor invasiveness, negatively regulating immune response, and changing the efficacy of certain anti-tumor drugs. It has been demonstrated that there are a large number of inflammatory factors and inflammatory cells in the tumor microenvironment, and tumor-promoting immunity and anti-tumor immunity exist simultaneously in the tumor microenvironment. The typical relationship between chronic inflammation and tumor has been presented by the relationships between

Indexed as

Big data analysisBiomarkersCancerChronic inflammationCollateral pathologiesEpigeneticsGeneticsGlobal statisticsIndividualized patient profileInflammatory factorsMachine learningModifiable and preventableMultiomicsPatient stratificationPhenotypingPredictive preventive personalized medicineRisk factors

Identifiers

PMID31832112
PMCPMC6882964
OpenAlexW2990476927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.