Evidence map›Paper›PMID 31831881›Full record

ArticleGenetics in medicine : official journal of the American College of Medical Genetics2020

Points to consider: is there evidence to support BRCA1/2 and other inherited breast cancer genetic testing for all breast cancer patients? A statement of the American College of Medical Genetics and Genomics (ACMG).

Tuya Pal, Doreen Agnese, Mary Daly, Albert La Spada, Jennifer Litton, Myra Wick, Susan Klugman, Edward D Esplin, Gail P Jarvik, Professional Practice and Guidelines Committee

Abstract read
PubMed Publisher
In one paragraph

Article in Genetics in medicine : official journal of the American College of Medical Genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Germline Pathogenic Variants in Cancer Predisposition Genes Among Women With Invasive Lobular Carcinoma of the Breast.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Article
  13. Breast Cancer Prevention: Time for Change.JCO oncology practice · 2021
    Article
  14. Article
  15. Article
  16. Review
  17. Evaluation of Germline Genetic Testing Criteria in a Hospital-Based Series of Women With Breast Cancer.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2020
    Article
  18. Germline genetic testing for breast cancer: which patients? What genes?Genetics in medicine : official journal of the American College of Medical Genetics · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Tuya PalDepartment of Medicine Division of Genetic Medicine, Vanderbilt University Medical Center/Vanderbilt-Ingram Cancer Center, Nashville, TN, USA.
Doreen AgneseDepartment of Internal Medicine Division of Surgical Oncology, The Ohio State University, Columbus, OH, USA.
Mary DalyDepartment of Clinical Genetics, Fox Chase Cancer Center, Philadelphia, PA, USA.
Albert La SpadaDepartments of Neurology, Neurobiology, and Cell Biology, Duke Center for Neurodegeneration & Neurotherapeutics, Duke University Medical Center, Durham, NC, USA.
Jennifer LittonDepartment of Breast Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Myra WickDepartments of Obstetrics and Gynecology and Clinical Genomics, Mayo Clinic, Rochester, MN, USA.
Susan KlugmanDepartment of Obstetrics & Gynecology and Women's Health, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.
Edward D EsplinInvitae Laboratory, San Francisco, CA, USA.
Gail P JarvikDepartments of Medicine (Medical Genetics) and Genome Sciences, University of Washington Medical Center, Seattle, WA, USA.
Professional Practice and Guidelines Committee

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Breast NeoplasmsGenetics, MedicalBRCA1 ProteinBRCA2 ProteinGenetic Predisposition to DiseaseGenetic TestingGenomicsHumansUnited StatesBRCA1 ProteinBRCA1 protein, humanBRCA2 ProteinBRCA1BRCA2breast cancergenetic testingmultigene panels

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.