ArticleScientific reports2019
Effects of disease, antibiotic treatment and recovery trajectory on the microbiome of farmed seabass (Dicentrarchus labrax).
Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 93 citations in OpenAlex.
- Host genotype and environmental factors differentially shape the black piranha's gill microbiota.Microbiology spectrum · 2026Article
- Vibrio proteolyticus DCF12.2 postbiotic modulates intestinal metabolic and immune pathways in zebrafish.Applied microbiology and biotechnology · 2026Article
- Gut microbiota remodeling and immune gene modulation byFrontiers in immunology · 2026Article
- Skin and gill microbiome profiles and network structures in farmed tilapia (Oreochromis niloticus) and their relationships with health conditions.Animal microbiome · 2025Article
- Impacts of environmentally relevant concentrations of antibiotic cocktails on the skin microbiome of Eurasian carp (Cyprinus carpio).Animal microbiome · 2025Article
- The nasal microbiota of two marine fish species: diversity, community structure, variability, and first insights into the impacts of climate change-related stressors.FEMS microbiology ecology · 2025Article
- The ecology and plasticity of fish skin and gill microbiomes: seeking what matters in health and disease.FEMS microbiology reviews · 2025Review
- Microbial community structure and functional characteristics across the mucosal surfaces of olive flounder (Frontiers in microbiology · 2025Article
- Analyzing bacterial networks and interactions in skin and gills of Sparus aurata with microalgae-based additive feeding.Scientific reports · 2024Article
- Understanding the role of microbes in health and disease of farmed aquatic organisms.Marine life science & technology · 2024Article
- Correlation Analysis of the Transcriptome and Gut Microbiota inMicroorganisms · 2024Article
- Association of microbial community structure with gill disease in marine-stage farmed Atlantic salmon (Salmo salar); a yearlong study.BMC veterinary research · 2024Article
- Influence of host phylogeny and water physicochemistry on microbial assemblages of the fish skin microbiome.FEMS microbiology ecology · 2024Article
- Article
- When the host's away, the pathogen will play: the protective role of the skin microbiome during hibernation.Animal microbiome · 2023Review
- Persistent Dysbiosis, Parasite Rise and Growth Impairment in Aquacultured European Seabass after Oxytetracycline Treatment.Microorganisms · 2023Article
- Sex-dependent effects of mechanical delousing on the skin microbiome of broodstock Atlantic salmon (Salmo salar L.).Scientific reports · 2023Article
- Effect of Copper Sulphate Exposure on the Oxidative Stress, Gill Transcriptome and External Microbiota of Yellow Catfish,Antioxidants (Basel, Switzerland) · 2023Article
- Hybrid of Metapenaeus dobsoni lectin and platinum nanoparticles exert antimicrobial and immunostimulatory effects to reduce bacterial bioburden in infected Nile tilapia.Scientific reports · 2023Article
- From a cell model to a fish trial: Immunomodulatory effects of heat-killed LactiplantibacillusFrontiers in immunology · 2023Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mucosal surfaces of fish harbour microbial communities that can act as the first-line of defense against pathogens. Infectious diseases are one of the main constraints to aquaculture growth leading to huge economic losses. Despite their negative impacts on microbial diversity and overall fish health, antibiotics are still the method of choice to treat many such diseases. Here, we use 16 rRNA V4 metataxonomics to study over a 6 week period the dynamics of the gill and skin microbiomes of farmed seabass before, during and after a natural disease outbreak and subsequent antibiotic treatment with oxytetracycline. Photobacterium damselae was identified as the most probable causative agent of disease. Both infection and antibiotic treatment caused significant, although asymmetrical, changes in the microbiome composition of the gills and skin. The most dramatic changes in microbial taxonomic abundance occurred between healthy and diseased fish. Disease led to a decrease in the bacterial core diversity in the skin, whereas in the gills there was both an increase and a shift in core diversity. Oxytetracycline caused a decrease in core diversity in the gill and an increase in the skin. Severe loss of core diversity in fish mucosae demonstrates the disruptive impact of disease and antibiotic treatment on the microbial communities of healthy fish.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.