ArticleNature communications2019
Audio-visual experience strengthens multisensory assemblies in adult mouse visual cortex.
Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 68 citations in OpenAlex.
- Selective weakening of population-coupled synaptic activity in vivo in a mouse model of amyloid-beta pathology.Nature communications · 2026Article
- Increased Perceptual Reliability Reduces Membrane Potential Variability in Cortical Neurons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Distinct Cortical Populations Drive Multisensory Modulation of Segregated Auditory Sources.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Auditory cortex learns to discriminate audiovisual cues through selective multisensory enhancement.eLife · 2025Article
- Article
- Multisensory Stimulation in Rehabilitation of Dementia: A Systematic Review.Biomedicines · 2025Review
- Brain-inspired multisensory integration neural network for cross-modal recognition through spatiotemporal dynamics and deep learning.Cognitive neurodynamics · 2024Article
- Network state changes in sensory thalamus represent learned outcomes.Nature communications · 2024Article
- Stability of cross-sensory input to primary somatosensory cortex across experience.bioRxiv : the preprint server for biology · 2024Article
- Auditory cortex conveys non-topographic sound localization signals to visual cortex.Nature communications · 2024Article
- Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex.Nature neuroscience · 2024Article
- Sound suppresses earliest visual cortical processing after sight recovery in congenitally blind humans.Communications biology · 2024Article
- The Development of Multisensory Integration at the Neuronal Level.Advances in experimental medicine and biology · 2024Article
- Age-related dysregulation of homeostatic control in neuronal microcircuits.Nature neuroscience · 2023Article
- Widefield imaging of rapid pan-cortical voltage dynamics with an indicator evolved for one-photon microscopy.Nature communications · 2023Article
- How 'visual' is the visual cortex? The interactions between the visual cortex and other sensory, motivational and motor systems as enabling factors for visual perception.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Multisensory integration in the mammalian brain: diversity and flexibility in health and disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023Review
- Coherent mapping of position and head direction across auditory and visual cortex.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Single neurons in the human medial temporal lobe flexibly shift representations across spatial and memory tasks.Hippocampus · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
We experience the world through multiple senses simultaneously. To better understand mechanisms of multisensory processing we ask whether inputs from two senses (auditory and visual) can interact and drive plasticity in neural-circuits of the primary visual cortex (V1). Using genetically-encoded voltage and calcium indicators, we find coincident audio-visual experience modifies both the supra and subthreshold response properties of neurons in L2/3 of mouse V1. Specifically, we find that after audio-visual pairing, a subset of multimodal neurons develops enhanced auditory responses to the paired auditory stimulus. This cross-modal plasticity persists over days and is reflected in the strengthening of small functional networks of L2/3 neurons. We find V1 processes coincident auditory and visual events by strengthening functional associations between feature specific assemblies of multimodal neurons during bouts of sensory driven co-activity, leaving a trace of multisensory experience in the cortical network.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.