Evidence map›Paper›PMID 31831200›Full record

Trial reportPsychiatry research2020

The role of negative affect in the association between attention bias to threat and posttraumatic stress: An eye-tracking study.

Yara Mekawi, Lauren Murphy, Adam Munoz, Maria Briscione, Erin B Tone, Seth D Norrholm, Tanja Jovanovic, Bekh Bradley, Abigail Powers

Abstract readClinical Trial
In one paragraph

Trial report in Psychiatry research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Trait-related neural basis of attentional bias to emotions: a tDCS study.Cognitive, affective & behavioral neuroscience · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yara MekawiDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America. Electronic address: yara.mekawi@emory.edu.
Lauren MurphyDepartment of Psychology, Emory University, Georgia, United States of America.
Adam MunozDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America.
Maria BriscioneDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America.
Erin B ToneDepartment of Psychology, Georgia State University, Georgia, United States of America.
Seth D NorrholmAtlanta VA Medical Center, Georgia, United States of America; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America.
Tanja JovanovicDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America.
Bekh BradleyDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America; Atlanta VA Medical Center, Georgia, United States of America.
Abigail PowersDepartment of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Georgia, United States of America.

Funding

Genetic and Trauma-Related Risk Factors for PTSDR01MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2005 to 2014
$8.5M
Mechanisms of Intergenerational Impact of Maternal TraumaR01HD071982 · NICHD · EMORY UNIVERSITY · PI BRADLEY, BEKH · 2013 to 2017
$2.1M
Development, Trauma, and Genotype Effects on Biomarkers of Anxiety in ChildrenR01MH100122 · NIMH · EMORY UNIVERSITY · PI JOVANOVIC, TANJA · 2013 to 2017
$1.9M
Primary-Care Based Mindfulness Intervention for Chronically Traumatized IndividualsK23AT009713 · NCCIH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2018 to 2021
$538k
Genetic and Trauma-Related Risk Factors for PTSD: From GWAS to FunctionR56MH071537 · NIMH · EMORY UNIVERSITY · PI RESSLER, KERRY J. · 2015 to 2015
$148k
The role of emotion dysregulation in PTSD symptomologyF32MH102890 · NIMH · EMORY UNIVERSITY · PI LOTT, ABIGAIL POWERS · 2014 to 2015
$102k
NCCIH NIH HHS K23 AT009713NICHD NIH HHS R01 HD071982NIMH NIH HHS F32 MH102890NIMH NIH HHS R01 MH071537NIMH NIH HHS R01 MH100122NIMH NIH HHS R56 MH071537
6 · The paper itself

Abstract

Biased processing of threatening stimuli, including attention toward and away from threat, has been implicated in the development and maintenance of PTSD symptoms. Research examining theoretically-derived mechanisms through which dysregulated processing of threat may be associated with PTSD is scarce. Negative affect, a transdiagnostic risk factor for many types of psychopathology, is one potential mechanism that has yet to be examined. Thus, the present study (n = 92) tested the indirect effect of attention bias on PTSD via negative affect using rigorous eye-tracking methodology in a sample of urban-dwelling, trauma-exposed African-American women. We found support for the hypothesis that attention bias toward threat was indirectly associated with PTSD symptoms through increased negative affect. These results suggest that negative affect may be an important etiological process through which attention bias patterns could impact PTSD symptom severity. Implications for psychological and pharmacological therapeutic interventions targeting threat-related attention biases and negative affect are discussed.

Indexed as

AffectAttentional BiasEye MovementsAdolescentAdultBlack or African AmericanCase-Control StudiesFemaleHumansMiddle AgedNegativismPhotic StimulationRisk FactorsStress Disorders, Post-TraumaticYoung AdultAttention biasEye-trackingNegative affectPTSD symptoms

Identifiers

PMID31831200
PMCPMC7012707

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.