Evidence map›Paper›PMID 31831005›Full record

ArticleNutrition journal2019

Adherence to the low carbohydrate diet and the risk of breast Cancer in Iran.

Bahareh Sasanfar, Fatemeh Toorang, Ahmad Esmaillzadeh, Kazem Zendehdel

Abstract read
In one paragraph

Article in Nutrition journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bahareh SasanfarCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, P.O. Box: 13145158, Tehran, Iran.
Fatemeh ToorangCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, P.O. Box: 13145158, Tehran, Iran.
Ahmad EsmaillzadehDepartment of Community Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran. a-esmaillzadeh@tums.ac.ir.
Kazem ZendehdelCancer Research Center, Cancer Institute of Iran, Tehran University of Medical Sciences, P.O. Box: 13145158, Tehran, Iran. kzendeh@tums.ac.ir.ORCID 0000-0002-0269-4945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPrevious studies on the link between macronutrients and breast cancer have mostly focused on individual macronutrients rather than their combination. This study investigates the association between adherence to a low carbohydrate diet and odds of breast cancer among women.

methodsThis hospital-based case-control study was carried out on 412 women with pathologically confirmed breast cancer within the past year and 456 apparently healthy controls that were matched in terms of age and residential place. Dietary data was collected using a 168-item validated FFQ. Participants were classified in terms of quintiles of percentages of energy intake from carbohydrates, proteins, and fats. Then, individuals in the highest quintile of fat and protein intake were given a score of 5 and those in the lowest quintile of these macronutrients were given a score of 1. Participants in the other quintiles of these macronutrients were given the corresponding score. In terms of carbohydrate intake, those in the highest quintile received a score of 1 and those in the lowest quintile received 5. The scores were then summed up to calculate the total low carbohydrate diet (LCD) score, which varied from 3 to 15. A higher score meant greater adherence to a low carbohydrate diet.

resultsThe mean age of study participants was 45.2 y and mean BMI was 28.4 kg/m

conclusionAdherence to LCD may be associated with increased odds of breast cancer in postmenopausal women. Prospective cohort studies are needed to confirm these findings.

Indexed as

AdultAgedAged, 80 and overBreast NeoplasmsCase-Control StudiesDiet, Carbohydrate-RestrictedFemaleHumansIranMiddle AgedPatient ComplianceRiskSurveys and QuestionnairesYoung AdultBreast cancerCarbohydrateDietFatMacronutrientProtein

Identifiers

PMID31831005
PMCPMC6909448

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.