ArticleMicrobial cell factories2019
Process engineering of pH tolerant Ustilago cynodontis for efficient itaconic acid production.
Article in Microbial cell factories, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 44 citations in OpenAlex.
- In situ product removal via reactive extraction in itaconic acid fermentation with Ustilago cynodontis.Biotechnology for biofuels and bioproducts · 2026Article
- From beet molasses to malic acid: holistic development of fermentation and downstream process.Biotechnology for biofuels and bioproducts · 2026Article
- Selective production of the itaconic acid-derived compounds 2-hydroxyparaconic and itatartaric acid.Metabolic engineering communications · 2024Article
- Balancing pH and yield: exploring itaconic acid production in Ustilago cynodontis from an economic perspective.Biotechnology for biofuels and bioproducts · 2024Article
- Itaconate Production from Crude Substrates with U. maydis: Scale-up of an Industrially Relevant Bioprocess.Microbial cell factories · 2024Article
- Exploitation of microbial activities at low pH to enhance planetary health.FEMS microbiology reviews · 2024Article
- Establishing an itaconic acid production process with Ustilago species on the low-cost substrate starch.FEMS yeast research · 2024Article
- In situ adsorption of itaconic acid from fermentations of Ustilago cynodontis improves bioprocess efficiency.Biotechnology for biofuels and bioproducts · 2023Article
- Development of an itaconic acid production process with Ustilaginaceae on alternative feedstocks.BMC biotechnology · 2023Article
- Holistic Approach to Process Design and Scale-Up for Itaconic Acid Production from Crude Substrates.Bioengineering (Basel, Switzerland) · 2023Article
- Respiration-based investigation of adsorbent-bioprocess compatibility.Biotechnology for biofuels and bioproducts · 2023Article
- Improved Itaconate Production withJournal of fungi (Basel, Switzerland) · 2022Article
- Effect of process mode, nitrogen source and temperature on L-malic acid production withFrontiers in bioengineering and biotechnology · 2022Article
- Enhanced l-Malic Acid Production byFrontiers in bioengineering and biotechnology · 2021Article
- An OptimizedJournal of fungi (Basel, Switzerland) · 2020Article
- Consolidated bioprocessing of cellulose to itaconic acid by a co-culture of Trichoderma reesei and Ustilago maydis.Biotechnology for biofuels · 2020Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundUstilago cynodontis ranks among the relatively unknown itaconate production organisms. In comparison to the well-known and established organisms like Aspergillus terreus and Ustilago maydis, genetic engineering and first optimizations for itaconate production were only recently developed for U. cynodontis, enabling metabolic and morphological engineering of this acid-tolerant organism for efficient itaconate production. These engineered strains were so far mostly characterized in small scale shaken cultures.
resultsIn pH-controlled fed-batch experiments an optimum pH of 3.6 could be determined for itaconate production in the morphology-engineered U. cynodontis Δfuz7. With U. cynodontis ∆fuz7
conclusionsHere, we characterize engineered U. cynodontis strains in controlled bioreactors and optimize the fermentation process for itaconate production. The results obtained are discussed in a biotechnological context and show the great potential of U. cynodontis as an itaconate producing host.
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