Evidence map›Paper›PMID 31830867›Full record

ArticleJournal of neurotrauma2020

Kaempferol Treatment after Traumatic Brain Injury during Early Development Mitigates Brain Parenchymal Microstructure and Neural Functional Connectivity Deterioration at Adolescence.

Maxime Parent, Jyothsna Chitturi, Vijayalakshmi Santhakumar, Fahmeed Hyder, Basavaraju G Sanganahalli, Sridhar S Kannurpatti

Open access · greenAbstract read
In one paragraph

Article in Journal of neurotrauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. Pooled it
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  4. Review
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  6. Article
  7. Article
  8. Review
  9. Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023
    Article
  10. Dietary (Poly)phenols in Traumatic Brain Injury.International journal of molecular sciences · 2023
    Review
  11. Article
  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Maxime ParentDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Jyothsna ChitturiDepartment of Radiology, Rutgers Biomedical and Health Sciences-New Jersey Medical School, Newark, New Jersey.
Vijayalakshmi SanthakumarDepartment of Pharmacology, Physiology and Neuroscience, Rutgers Biomedical and Health Sciences-New Jersey Medical School, Medical Science Building, Newark, New Jersey.
Fahmeed HyderDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Basavaraju G SanganahalliDepartment of Radiology and Biomedical Imaging, Yale University School of Medicine, New Haven, Connecticut.
Sridhar S KannurpattiDepartment of Radiology, Rutgers Biomedical and Health Sciences-New Jersey Medical School, Newark, New Jersey.
Yale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NeurophysiologicP30NS052519 · NINDS · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2007 to 2017
$6.7M
Energetics of Neuronal Populations by fMRIR01MH067528 · NIMH · YALE UNIVERSITY · PI HYDER, DEWAN SYED FAHMEED · 2002 to 2021
$5.9M
Contribution of Innate Immune Receptors to Neurological Dysfunction After Traumatic Brain Injury: Mechanisms and Therapeutic ImplicationsR01NS097750 · NINDS · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI SANTHAKUMAR, VIJAYALAKSHMI · 2016 to 2025
$4.0M
Perisomatic Inhibitory Network Dysfunction in Neurological DiseaseR01NS069861 · NINDS · UNIV OF MED/DENT OF NJ-NJ MEDICAL SCHOOL · PI SANTHAKUMAR, VIJAYALAKSHMI · 2011 to 2022
$3.4M
NCATS NIH HHS UL1 TR001863NIMH NIH HHS R01 MH067528NINDS NIH HHS P30 NS052519NINDS NIH HHS R01 NS069861NINDS NIH HHS R01 NS097750
6 · The paper itself

Abstract

Targeting mitochondrial ion homeostasis using Kaempferol, a mitochondrial Ca

Indexed as

Age FactorsAnimalsBrainBrain Injuries, TraumaticKaempferolsMagnetic Resonance ImagingMaleNerve NetParenchymal TissueRatsRats, Sprague-DawleyTreatment OutcomekaempferolKaempferolsadolescenceconnectivityDTIfMRIKaempferoltraumatic brain injury

Identifiers

PMID31830867
PMCPMC7175625
OpenAlexW2996064407

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.