Evidence map›Paper›PMID 31830721›Full record

ArticleJournal of psychiatric research2020

Male-specific association of the 2p25 region with suicide attempt in bipolar disorder.

Sophia C Gaynor, Eric T Monson, Marie E Gaine, Michael S Chimenti, Rachel D Reichman, Meredith Parsons, Lalita Oonthonpan, Peter P Zandi, James B Potash, Virginia L Willour

Open access · greenAbstract read
In one paragraph

Article in Journal of psychiatric research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Investigating the Relationship Between DNA Methylation, Genetic Variation, and Suicide Attempt in Bipolar Disorder.Archives of suicide research : official journal of the International Academy for Suicide Research
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sophia C GaynorDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Eric T MonsonDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Marie E GaineMolecular Physiology and Biophysics, Iowa Neuroscience Institute, Carver College of Medicine, University of Iowa, Iowa City, IA, 52242, USA.
Michael S ChimentiBioinformatics Division, Iowa Institute of Human Genetics, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Rachel D ReichmanDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Meredith ParsonsDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Lalita OonthonpanDepartment of Biochemistry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA.
Peter P ZandiDepartment of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
James B PotashDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, 21287, USA.
Virginia L WillourDepartment of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, 52242, USA. Electronic address: virginia-willour@uiowa.edu.
University of Iowa · USJohns Hopkins University · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007337 · NIGMS · UNIVERSITY OF IOWA · PI GEYER, PAMELA K., LENTZ, STEVEN R · 1985 to 2020
$15.9M
PROGRAM IN HEMOSTASIS AND THROMBOSIS FOR ACADEMICT32HL007344 · NHLBI · UNIVERSITY OF IOWA · PI Anil Kumar Chauhan, Steven R Lentz · 1985 to 2026
$6.5M
Genetic Risk Factor Suicidal BehaviorR01MH079240 · NIMH · UNIVERSITY OF IOWA · PI WILLOUR, VIRGINIA L · 2007 to 2015
$3.5M
NHLBI NIH HHS T32 HL007344NIGMS NIH HHS T32 GM007337NIMH NIH HHS R01 MH079240
6 · The paper itself

Abstract

We previously conducted a genome-wide association study (GWAS) of attempted suicide within bipolar disorder, which implicated common variation in the 2p25 region primarily in males. The top association signal from our GWAS occurred in an intergenic region of 2p25 (p = 5.07 × 10

Indexed as

Suicide, AttemptedAdolescentAdultAgedAged, 80 and overBipolar DisorderChromosomes, Human, Pair 2FemaleGenome-Wide Association StudyHigh-Throughput Nucleotide SequencingHumansLinkage DisequilibriumMaleMiddle AgedQuantitative Trait LociSequence Analysis, DNA2p25BipolarGeneticsSequencingSex-specificSuicide

Identifiers

PMID31830721
PMCPMC8344384
OpenAlexW2987829702

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.