Evidence map›Paper›PMID 31829919›Full record

ArticleEmerging infectious diseases2020

Exposure to Ebola Virus and Risk for Infection with Malaria Parasites, Rural Gabon.

Jessica L Abbate, Pierre Becquart, Eric Leroy, Vanessa O Ezenwa, Benjamin Roche

Open access · diamondAbstract read
In one paragraph

Article in Emerging infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 4 countries.

Jessica L Abbate
Pierre Becquart
Eric Leroy
Vanessa O Ezenwa
Benjamin Roche
Maladies Infectieuses et Vecteurs: Écologie, Génétique, Évolution et Contrôle · FRAgropolis International · FRUniversidad Nacional Autónoma de México · MXUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An association between malaria and risk for death among patients with Ebola virus disease has suggested within-host interactions between Plasmodium falciparum parasites and Ebola virus. To determine whether such an interaction might also influence the probability of acquiring either infection, we used a large snapshot surveillance study from rural Gabon to test if past exposure to Ebola virus is associated with current infection with Plasmodium spp. during nonepidemic conditions. We found a strong positive association, on population and individual levels, between seropositivity for antibodies against Ebola virus and the presence of Plasmodium parasites in the blood. According to a multiple regression model accounting for other key variables, antibodies against Ebola virus emerged as the strongest individual-level risk factor for acquiring malaria. Our results suggest that within-host interactions between malaria parasites and Ebola virus may underlie epidemiologic associations.

Indexed as

AdolescentAdultEbolavirusFemaleGabonHemorrhagic Fever, EbolaHost-Parasite InteractionsHumansMalaria, FalciparumMaleMiddle AgedPlasmodium falciparumRisk FactorsRural PopulationSurveys and QuestionnairesYoung AdultdiseaseEbola virusecologyepidemiologyGabonmalariaoccurrenceparasitespathogen-pathogen interactionsPlasmodiumpopulations at riskprevalencerisk factorssurveillanceviruses

Identifiers

PMID31829919
PMCPMC6986822
OpenAlexW2997207775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.