Evidence map›Paper›PMID 31829784›Full record

ReviewScience progress2019

Endocrine disrupting chemicals: Impact on human health, wildlife and the environment.

Telma Encarnação, Alberto Acc Pais, Maria G Campos, Hugh D Burrows

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Science progress, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 3 pooled it
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 3 syntheses or guidelines pooled it, 201 citations in OpenAlex.

  1. Association between exposure to endocrine-disrupting chemicals and polycystic ovary syndrome: a systematic review.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Pooled it
  2. Pooled it
  3. Pooled it
  4. AI/ML-based computational models for toxicity prediction.Environmental science and pollution research international · 2026
    Review
  5. Review
  6. Endocrine Disruption and Male Fertility.Current environmental health reports · 2026
    Review
  7. Article
  8. Article
  9. Bisphenols and follicle function in farm species.The Journal of reproduction and development · 2026
    Review
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  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Telma EncarnaçãoCQC, Department of Chemistry, University of Coimbra, Coimbra, Portugal.
Alberto Acc PaisCQC, Department of Chemistry, University of Coimbra, Coimbra, Portugal.
Maria G CamposCQC, Department of Chemistry, University of Coimbra, Coimbra, Portugal.
Hugh D BurrowsCQC, Department of Chemistry, University of Coimbra, Coimbra, Portugal.
University of Coimbra · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endocrine disrupting chemicals are a group of pollutants that can affect the endocrine system and lead to diseases and dysfunctions across the lifespan of organisms. They are omnipresent. They are in the air we breathe, in the food we eat and in the water we drink. They can be found in our everyday lives through personal care products, household cleaning products, furniture and in children's toys. Every year, hundreds of new chemicals are produced and released onto the market without being tested, and they reach our bodies through everyday products. Permanent exposure to those chemicals may intensify or even become the main cause for the development of diseases such as type 2 diabetes, obesity, cardiovascular diseases and certain types of cancer. In recent years, legislation and regulations have been implemented, which aim to control the release of potentially adverse endocrine disrupting chemicals, often invoking the precautionary principle. The objective of this review is to provide an overview of research on environmental aspects of endocrine disrupting chemicals and their effects on human health, based on evidence from animal and human studies. Emphasis is given to three ubiquitous and persistent groups of chemicals, polychlorinated biphenyls, polybrominated diphenyl ethers and organochlorine pesticides, and on two non-persistent, but ubiquitous, bisphenol A and phthalates. Some selected historical cases are also presented and successful cases of regulation and legislation described. These led to a decrease in exposure and consequent minimization of the effects of these compounds. Recommendations from experts on this field, World Health Organization, scientific reports and from the Endocrine Society are included.

Indexed as

Animals, WildEnvironmental MonitoringAnimalsEndocrine DisruptorsEnvironmental PollutantsHumansEndocrine DisruptorsEnvironmental PollutantschildrenEndocrine disruptionenvironmenthuman healthpolicyprecautionary principle

Identifiers

PMID31829784
PMCPMC10424550
OpenAlexW2924724409

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.