Evidence map›Paper›PMID 31829769›Full record

ArticleGut microbes2020

The YrbE phospholipid transporter of

Smriti Verma, Rachel A Prescott, Laura Ingano, Kourtney P Nickerson, Emily Hill, Christina S Faherty, Alessio Fasano, Stefania Senger, Bobby J Cherayil

Open access · goldAbstract read
In one paragraph

Article in Gut microbes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
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  7. Transcriptomic Analysis, Motility and Biofilm Formation Characteristics ofInternational journal of molecular sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Smriti VermaMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Rachel A PrescottMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.ORCID 0000-0001-6344-9241
Laura InganoMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Kourtney P NickersonMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Emily HillMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Christina S FahertyMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.ORCID 0000-0002-3200-161X
Alessio FasanoMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Stefania SengerMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.ORCID 0000-0002-3356-2689
Bobby J CherayilMucosal Immunology and Biology Research Center, Department of Pediatrics, Massachusetts General Hospital , Boston, Massachusetts, USA.
Harvard University · USMassachusetts General Hospital · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Wild-type S. typhi Infection in Humans: Integrated Immunoprotective MechanismsU19AI082655 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SZTEIN, MARCELO B. · 2009 to 2018
$27.8M
Cross-talk between iron metabolism and intestinal inflammationR01AI089700 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI CHERAYIL, BOBBY JOSEPH · 2011 to 2020
$4.4M
MGHfC Digestive Disease Summer Research ProgramR25DK103579 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI BRYAN P HURLEY · 2015 to 2026
$1.2M
NIAID NIH HHS R01 AI089700NIAID NIH HHS U19 AI082655NIDDK NIH HHS P30 DK040561NIDDK NIH HHS R25 DK103579
6 · The paper itself

Abstract

salmonella entericaserovar Typhi is the etiologic agent of typhoid fever, a major public health problem in the developing world. Moving toward and adhering to the intestinal epithelium represents key initial steps of infection by

Indexed as

Bacterial AdhesionAnimalsBacterial ProteinsCells, CulturedDisease Models, AnimalDogsEpithelial CellsFlagellinGene Expression Regulation, BacterialHeLa CellsHost Microbial InteractionsHumansInflammationInterleukin-8MaleMembrane Transport ProteinsBacterial ProteinsCXCL8 protein, humanFlagellinInterleukin-8Membrane Transport ProteinsPhospholipidsadhesionepithelial cellsinflammationSalmonellatyphoid

Identifiers

PMID31829769
PMCPMC7527071
OpenAlexW2996219852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.