Evidence map›Paper›PMID 31829753›Full record

ArticleCurrent eye research2020

Real-world Outcomes among Eyes with Center-Involving Diabetic Macular Edema and Good Visual Acuity.

Sidra Zafar, Kerry Smith, Michael V Boland, Christina Y Weng, Sharon Solomon, Roomasa Channa

Abstract read
In one paragraph

Article in Current eye research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sidra ZafarWilmer Eye Institute, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Kerry SmithWilmer Eye Institute, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Michael V BolandWilmer Eye Institute, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Christina Y WengDepartment of Ophthalmology, Baylor College of Medicine , Houston, Texas, USA.
Sharon SolomonWilmer Eye Institute, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.
Roomasa ChannaWilmer Eye Institute, Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.

Funding

Wilmer Core Grant for Vision ResearchP30EY001765 · NEI · JOHNS HOPKINS UNIVERSITY · PI JEFFREY MUMM · 1985 to 2026
$22.1M
NEI NIH HHS P30 EY001765
6 · The paper itself

Abstract

purposeWe aimed to determine long-term visual and anatomical outcomes among patients with center involving-diabetic macular edema and good vision and evaluate factors associated with visual and anatomic outcomes. MATERIALS AND

methodsIn this retrospective study, all patients with type 2 diabetes aged ≥18 years had seen at the Wilmer Eye Institute between March 2015-June 2018 and with diabetic macular edema confirmed on spectral-domain optical coherence tomography imaging were included, provided they had visual acuity of 20/30 or better in ≥1 eye and a follow-up duration of ≥3 clinic visits. Change in logMAR visual acuity and central 1 mm foveal thickness from baseline, lines of visual acuity gained/lost for overall cohort stratified by treatment were analyzed.

resultsAmong 197 (243 eyes) participants, mean (± standard deviation) age was 63.4 ± 11.2 years, and half were males. Average duration of follow-up was 1.7 ± 0.7 years. One hundred and forty-six eyes (60%) received anti-vascular endothelial growth factor injections, at an average of 3.7 ± 2.9 injections/eye/year. Mean logMAR visual acuity at baseline was 0.1 ± 0.1 [Snellen 20/25] in both treatment and observation (no anti-vascular endothelial growth factor treatment received during and 3 months prior to the study inclusion period) groups. Final logMAR visual acuity was 0.2 ± 0.2 in the treatment group [Snellen 20/32] versus 0.1 ± 0.3 in observation group [Snellen 20/25]; (

conclusionsAfter an average of 1.7 years of follow-up, there were no significant differences in final vision or central foveal thickness irrespective of whether patients received or did not receive treatment with anti-vascular endothelial growth factor injections.

Indexed as

Laser CoagulationVitrectomyAdultAgedAged, 80 and overAngiogenesis InhibitorsDiabetes Mellitus, Type 2Diabetic RetinopathyFemaleFollow-Up StudiesHumansIntravitreal InjectionsMacular EdemaMaleMiddle AgedRetrospective StudiesAngiogenesis InhibitorsVascular Endothelial Growth Factor AVEGFA protein, humanagencies regulationanti-VEGFCi-DMEgood visionobservation

Identifiers

PMID31829753
PMCPMC10407997

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.