Evidence map›Paper›PMID 31829227›Full record

Trial reportScandinavian journal of trauma, resuscitation and emergency medicine2019

The cost-effectiveness of upfront point-of-care testing in the emergency department: a secondary analysis of a randomised, controlled trial.

Lara Nicole Goldstein, Mike Wells, Craig Vincent-Lambert

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Scandinavian journal of trauma, resuscitation and emergency medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03102216 (An Assessment of the Impact of Enhanced Workflow Patterns Associated With Upfront, Early Point-of-care Testing on Costs, Waiting and Disposition Times in an Emergency Department), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03102216 nacompletednot on this map

An Assessment of the Impact of Enhanced Workflow Patterns Associated With Upfront, Early Point-of-care Testing on Costs, Waiting and Disposition Times in an Emergency Department

TypeinterventionalSponsorHelen Joseph HospitalRan2017 to 2017Enrolled1,134ConditionsEmergency Medicine, Point-of-Care TestingArmsiSTAT, CBC, ECG, Lodox
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Advances in laboratory medicine · 2025
    Article
  4. Transformative impact of point-of-care testing in critical care.World journal of critical care medicine · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Implementation of point-of-care blood gas testing at a large community hospital: Cost analysis, sepsis bundle compliance, and employee engagement.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lara Nicole GoldsteinDivision of Emergency Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa. drg666@gmail.com.ORCID http://orcid.org/0000-0002-9427-8710
Mike WellsDepartment of Emergency Medical Care, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-4520-2007
Craig Vincent-LambertDepartment of Emergency Medical Care, Faculty of Health Sciences, University of Johannesburg, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-7312-6654

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTime-saving is constantly sought after in the Emergency Department (ED), and Point-of-Care (POC) testing has been shown to be an effective time-saving intervention. However, when direct costs are compared, these tests commonly appear to be cost-prohibitive. Economic viability may become apparent when the time-saving is translated into financial benefits from staffing, time- and cost-saving. The purpose of this study was to evaluate the cost-effectiveness of diagnostic investigations utilised prior to medical contact for ED patients with common medical complaints.

methodsThis was a secondary analysis of data from a prospective, randomised, controlled trial in order to assess the cost-effectiveness of upfront, POC testing. Eleven combinations of POC equivalents of commonly-used special investigations (blood tests (i-STAT and complete blood count (CBC)), electrocardiograms (ECGs) and x-rays (LODOX® (Low Dose X-ray)) were evaluated compared to the standard ED pathway with traditional diagnostic tests. The economic viability of each permutation was assessed using the Incremental Cost Effectiveness Ratio and Cost-Effectiveness Acceptability Curves. Expenses related to the POC test implementation were compared to the control group while taking staffing costs and time-saving into account.

resultsThere were 897 medical patients randomised to receive various combinations of POC tests. The most cost-effective combination was the i-STAT+CBC permutation which, based on the time saving, would ultimately save money if implemented. All LODOX®-containing permutations were costlier but still saved time. Non-LODOX® permutations were virtually 100% cost-effective if an additional cost of US$50 per patient was considered acceptable. Higher staffing costs would make using POC testing even more economical.

conclusionsIn certain combinations, upfront, POC testing is more cost-effective than standard diagnostic testing for common ED undifferentiated medical presentations - the most economical POC test combination being the i-STAT + CBC. Upfront POC testing in the ED has the potential to not only save time but also to save money.

trial registrationClinicalTrials.gov: NCT03102216.

Indexed as

AdultCost-Benefit AnalysisEmergency Service, HospitalFemaleHumansMaleMiddle AgedPoint-of-Care TestingProspective StudiesEconomic analysisEmergency departmentPoint-of-care systemsPoint-of-care testing

Identifiers

PMID31829227
PMCPMC6907262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.