Evidence map›Paper›PMID 31829192›Full record

ArticleHealth and quality of life outcomes2019

The mediating role of sleep quality in the association between nocturia and health-related quality of life.

Edmond Pui Hang Choi, Eric Yuk Fai Wan, Jojo Yan Yan Kwok, Weng Yee Chin, Cindy Lo Kuen Lam

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Health and quality of life outcomes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.

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  16. A Comprehensive Community-Based Prevalence Study on Nocturia in Hong Kong Male Adults.International journal of environmental research and public health · 2021
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  19. Effects of spiritual resilience on psychological distress and health-related quality of life in Chinese people with Parkinson's disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Edmond Pui Hang ChoiSchool of Nursing, University of Hong Kong, 4/F, William M.W. Mong Block, 21 Sassoon Road, Pokfulam, Hong Kong. h0714919@connect.hku.hk.ORCID http://orcid.org/0000-0001-9062-3540
Eric Yuk Fai WanDepartment of Family Medicine and Primary Care, University of Hong Kong, Pokfulam, Hong Kong.
Jojo Yan Yan KwokSchool of Nursing, University of Hong Kong, 4/F, William M.W. Mong Block, 21 Sassoon Road, Pokfulam, Hong Kong.
Weng Yee ChinDepartment of Family Medicine and Primary Care, University of Hong Kong, Pokfulam, Hong Kong.
Cindy Lo Kuen LamDepartment of Family Medicine and Primary Care, University of Hong Kong, Pokfulam, Hong Kong.
Queen Mary Hospital · CNHKU-Pasteur Research Pole · HK

Funding

Seed Fund for Basic Research, HKU 201804159013
6 · The paper itself

Abstract

backgroundEven though the negative impacts of nocturia on sleep quality and health-related quality of life (HRQOL) have been documented in previous research, their interrelationship has been poorly studied. This study aimed to explore whether nocturia would affect sleep quality, which in turn affects HRQOL.

methodsParticipants aged 40 and above were randomly recruited from a Hong Kong public primary care clinic. Participants were asked to report the average number of nocturia (waking up at night to void) pisodes per night over a 1-month period. The Pittsburgh Sleep Quality Index (PSQI) and the 12-Item Short Form Health Survey version 2 (SF-12 v2) were administered. The mediation analysis was tested using multistage regression approach and bootstrap method.

resultsOf the 500 subjects who completed the survey, 31.2% reported symptomatic nocturia (having ≥2 nocturia episodes per night), and 60.4% experienced poor sleep quality (a PSQI global score > 5). Respondents with symptomatic nocturia had a poorer HRQOL in the domains of physical functioning (PF), role physical (RP) and social functioning (SF), general health (GH), vitality (VT) and physical component summary (PCS) of the SF-12 v2 than those without. Compared with the respondents without poor sleep quality, those with poor sleep quality had poorer HRQOL across all domains and summaries of the SF-12 v2. Mediation analysis found that sleep quality fully mediated the association between nocturia and the PF, RP and SF domains of the SF-12 v2, respectively, and partially mediated the association between nocturia and the GH, VT and PCS domains of the SF-12 v2, respectively.

conclusionsWe found that sleep quality mediated the association between nocturia and HRQOL. To enhance the HRQOL of patients with nocturia, clinicians should not only focus on nocturia symptoms, but also on their sleep quality.

Indexed as

Quality of LifeAdultAgedFemaleHealth SurveysHong KongHumansMaleMiddle AgedNocturiaSleepHealth-related quality of lifeMediationNocturiaSleep quality

Identifiers

PMID31829192
PMCPMC6907224
OpenAlexW2996023458

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.