Evidence map›Paper›PMID 31829179›Full record

SynthesisCardiovascular diabetology2019

Prognostic value of HbA1c for in-hospital and short-term mortality in patients with acute coronary syndrome: a systematic review and meta-analysis.

Wenjun Pan, Haining Lu, Baotao Lian, Pengda Liao, Liheng Guo, Minzhou Zhang

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Cardiovascular diabetology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. [Hospital diabetes management (Update 2026)].Wiener klinische Wochenschrift · 2026
    Guideline
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Wenjun PanGuangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Haining LuGuangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Baotao LianGuangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Pengda LiaoThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Liheng GuoThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China.
Minzhou ZhangThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou, 510120, China. minzhouzhang@aliyun.com.ORCID 0000-0001-5959-8367
Guangzhou University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHbA1c, the most commonly used indicator of chronic glucose metabolism, is closely associated with cardiovascular disease. However, the relationship between HbA1c and the mortality of acute coronary syndrome (ACS) patients has not been elucidated yet. Here, we aim to conduct a systematic review assessing the effect of HbA1c on in-hospital and short-term mortality in ACS patients.

methodsRelevant studies reported before July 2019 were retrieved from databases including PubMed, Embase, and Central. Pooled relative risks (RRs) and the corresponding 95% confidence interval (CI) were calculated to evaluate the predictive value of HbA1c for the in-hospital mortality and short-term mortality.

resultsData from 25 studies involving 304,253 ACS patients was included in systematic review. The pooled RR of in-hospital mortality was 1.246 (95% CI 1.113-1.396, p: 0.000, I

conclusionsHigher HbA1c is a potential indicator for in-hospital death in ACS patients as well as a predictor for short-term mortality in ACS patients without known DM and without DM.

Indexed as

Hospital MortalityAcute Coronary SyndromeAgedBiomarkersFemaleGlycated HemoglobinHumansMaleMiddle AgedPatient AdmissionPredictive Value of TestsPrognosisRisk AssessmentRisk FactorsTime FactorsBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanAcute coronary syndromeGlycated hemoglobin AMortalityPredictor

Identifiers

PMID31829179
PMCPMC6905004
OpenAlexW2995576550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.