Evidence map›Paper›PMID 31828733›Full record

ArticleJournal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology2020

Pre-exposure Prophylaxis Therapy and the Blood-Brain Barrier: Is PrEP Neuroprotective?

Joanna Kettlewell, Maya Barney, Robert Oda, Melissa Agsalda-Garcia, Chathura Siriwardhana, Bruce Shiramizu

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joanna KettlewellDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology; John A. Burns School of Medicine, University of Hawaii, 651 Ilalo St., Biosciences Building 325, Honolulu, HI, 96813, USA.
Maya BarneyHawaii Center for AIDS, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.
Robert OdaDepartment of Molecular Biosciences and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.
Melissa Agsalda-GarciaDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology; John A. Burns School of Medicine, University of Hawaii, 651 Ilalo St., Biosciences Building 325, Honolulu, HI, 96813, USA.
Chathura SiriwardhanaDepartment of Quantitative Health Sciences, John A. Burns School of Medicine Biostatistics Core Facility; John A. Burns School of Medicine, University of Hawaii, Honolulu, HI, USA.
Bruce ShiramizuDepartment of Tropical Medicine, Medical Microbiology, and Pharmacology; John A. Burns School of Medicine, University of Hawaii, 651 Ilalo St., Biosciences Building 325, Honolulu, HI, 96813, USA. bshirami@hawaii.edu.ORCID 0000-0002-9833-0256

Funding

The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Jerris Robert Hedges · 2017 to 2026
$59.5M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI HEDGES, JERRIS ROBERT, MOKUAU, NOREEN · 2012 to 2018
$21.1M
Small Grants ProgramP30GM114737 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI NERURKAR, VIVEK RAMCHANDRA · 2015 to 2022
$8.1M
Maraviroc and NeuroAIDS PathogenesisR01MH102196 · NIMH · UNIVERSITY OF HAWAII AT MANOA · PI SHIKUMA, CECILIA M., SHIRAMIZU, BRUCE T · 2014 to 2018
$3.5M
NIGMS NIH HHS P30 GM114737NIMHD NIH HHS U54 MD007584NIMHD NIH HHS U54 MD007601NIMH NIH HHS R01 MH102196
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAnti-HIV AgentsBlood-Brain BarrierEmtricitabineHumansMonocytesNeuroprotective AgentsPre-Exposure ProphylaxisTenofovirAnti-HIV AgentsEmtricitabineNeuroprotective AgentsTenofovir

Identifiers

PMID31828733
PMCPMC7141950

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.