Evidence map›Paper›PMID 31828537›Full record

ArticleJournal of cardiovascular translational research2020

Echocardiographic Left Ventricular Mass Estimation: Two-Dimensional Area-Length Method is Superior to M-Mode Linear Method in Swine Models of Cardiac Diseases.

Satoshi Miyashita, Nadjib Hammoudi, Shin Watanabe, Olympia Bikou, Kelly Yamada, Jaume Aguero, Koichi Nomoto, Taro Kariya, Kenneth Fish, Roger J Hajjar and 1 more

Abstract read
In one paragraph

Article in Journal of cardiovascular translational research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Satoshi MiyashitaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Nadjib HammoudiCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Shin WatanabeCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Olympia BikouCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kelly YamadaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Jaume AgueroCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Koichi NomotoCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Taro KariyaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Kenneth FishCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Roger J HajjarPhospholamban Foundation, Amsterdam, NL, Netherlands.
Kiyotake IshikawaCardiovascular Research Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA. kiyotake.ishikawa@mssm.edu.ORCID 0000-0002-8287-3483

Funding

TRIP: Targeted Gene Therapy for the Treatment of Heart FailureP50HL112324 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ASCHEIM, DEBORAH DAVIS, HAJJAR, ROGER J. · 2012 to 2014
$6.4M
Percutaneous Left Ventricular Unloading for Cardiogenic Shock: Beyond Acute Hemodynamic SupportR01HL139963 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kiyotake Ishikawa · 2018 to 2026
$4.9M
Therapeutic Mechanisms of Cardiac Progenitors in Ischemic CardiomyopathyR01HL135093 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI FISH, KENNETH MICHAEL, KOVACIC, JASON CIRIL · 2017 to 2020
$3.4M
SUMO1 and SERCA2a FunctionR01HL117505 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WEBER, THOMAS · 2013 to 2020
$3.4M
Anti-AAV Antibodies as an Obstacle to Cardiac AAV Gene TherapyR01HL131404 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI WEBER, THOMAS · 2016 to 2019
$3.3M
Calcium Pump Activators for Heart Failure TherapyR01HL129814 · NHLBI · UNIVERSITY OF MINNESOTA · PI THOMAS, DAVID D · 2015 to 2018
$3.2M
Targeting Abnormal Calcium Cycling Using Novel Gene Therapy VectorsR01HL119046 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI AKAR, FADI GABRIEL, HAJJAR, ROGER J. · 2014 to 2017
$2.9M
Role of miR25 in Heart FailureR01HL128072 · NHLBI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI HAJJAR, ROGER J., MERCOLA, MARK · 2015 to 2018
$2.5M
NHLBI NIH HHS P50 HL112324NHLBI NIH HHS R01 HL117505NHLBI NIH HHS R01 HL119046NHLBI NIH HHS R01 HL128072NHLBI NIH HHS R01 HL129814NHLBI NIH HHS R01 HL131404NHLBI NIH HHS R01 HL135093NHLBI NIH HHS R01 HL139963
6 · The paper itself

Abstract

Echocardiography offers rapid and cost-effective estimations of left ventricular (LV) mass, but its accuracy in patients with cardiac disease remains unclear. LV mass was measured by M-mode-based linear method and two-dimensional echocardiography (2DE)-based area-length method in pig models and correlation with actual LV weight was assessed. Twenty-six normal, 195 ischemic heart disease (IHD), and 33 non-IHD HF pigs were included. A strong positive linear relationship to the actual LV weight was found with 2DE-based area-length method (r = 0.82, p < 0.001), whereas a moderate relationship was found with M-mode method in the overall population (r = 0.68, p < 0.001). Two correlation coefficients were significantly different (p < 0.001), and were driven mainly by incremental overestimation of LV mass in heavier hearts using the M-mode method. IHD and LV dilation were the factors contributing to overestimation using M-mode method. 2DE-based area-length method provides a better estimation of LV weight in swine models of HF, particularly in those with IHD.

Indexed as

EchocardiographyVentricular Function, LeftVentricular RemodelingAnimalsDisease Models, AnimalFemaleHypertrophy, Left VentricularMaleMyocardial InfarctionObserver VariationPredictive Value of TestsReproducibility of ResultsSus scrofaCardiac diseaseDilationEchocardiographyHeart massHypertrophyInfarctionScar

Identifiers

PMID31828537
PMCPMC7286771

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.