ArticleLung2020
Risk of Readmission and Mortality Following Hospitalization with Hypercapnic Respiratory Failure.
Article in Lung, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 42 citations in OpenAlex.
- Health Communication and Adherence to Noninvasive Ventilation in Chronic Hypercapnic Respiratory Failure: A Randomized Clinical Trial.JAMA network open · 2024Trial
- Article
- Acute hYpErcapnic respiratory failure in The ICU: A multicenter prospective observational study - The YETI study.Annals of intensive care · 2026Article
- The Consistency of Hypercapnic Respiratory Failure Case Definitions in Electronic Health Record Data.Chest · 2026Article
- Metabolomic biomarkers predict long-term physical function in survivors of acute respiratory failure.Respiratory research · 2025Article
- Metabolomic Biomarkers Predict Long-term Physical Function in Survivors of Acute Respiratory Failure.Research square · 2025Article
- Article
- Association between body roundness index and lung function among U.S. adults.BMC public health · 2025Article
- Physiological effects and clinical evidence of high-flow nasal cannula during acute exacerbation in COPD patients: A narrative review.Journal of intensive medicine · 2025Review
- Comparing Nurse-Led and Physician-Led Bilevel Positive Airway Pressure Management in Hypercapnic Respiratory Failure: A Retrospective Cohort Study.Nursing open · 2025Article
- Unmasking the Complex Interplay of Obesity Hypoventilation Syndrome, Heart Failure, and Sleep Dysfunction: A Physiological and Psychological Perspective in a Digital Health World.Behavioral sciences (Basel, Switzerland) · 2025Review
- Breaking new ground: machine learning enhances survival forecasts in hypercapnic respiratory failure.Frontiers in medicine · 2025Article
- Post-Discharge non-invasive ventilation for hypercapnic respiratory failure: Outcomes in a Rural Cohort.PloS one · 2025Article
- Nutritional and Inflammatory Predictors of All-Cause Mortality in COPD Patients with Hypercapnic Respiratory Failure: A Two-Center Prospective Cohort Study.International journal of chronic obstructive pulmonary disease · 2025Observational
- Long-term cohort study of patients presenting with hypercapnic respiratory failure.BMJ open respiratory research · 2024Article
- The Role of Obstructive Sleep Apnea in Hypercapnic Respiratory Failure Identified in Critical Care, Inpatient, and Outpatient Settings.Sleep medicine clinics · 2024Review
- Exploring the impact of OSA on short-term survival in patients with AECOPD admitted to the ICU.PloS one · 2024Article
- What Are We Aiming for in Chronic Hypercapnic Respiratory Failure?Respiratory care · 2023Article
- Causes of hypercapnic respiratory failure: a population-based case-control study.BMC pulmonary medicine · 2023Article
- Causes of hypercapnic respiratory failure and associated in-hospital mortality.Respirology (Carlton, Vic.) · 2023Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeHypercapnic respiratory failure (HRF) is a frequent cause of hospitalization and a common comorbidity in hospitalized patients. There are few studies addressing what factors might predict poor outcomes in this patient population. The purpose of the current study was to investigate characteristics and outcomes of patients hospitalized with HRF.
methodsA study of patients ≥ 18 years admitted with HRF in a 1-year period. Patients with limited life expectancy related to other conditions, and those with a non-respiratory cause of HRF, were excluded.
results202 subjects met eligibility criteria: 24% had a diagnosis of obstructive sleep apnea, 6% obesity hypoventilation, 46% chronic obstructive pulmonary disease, and 10% asthma. Fifteen (7%) died during the index admission. Forty-one patients (23%) were readmitted within 30 days: peripheral vascular disease [adjusted odds ratio (aOR) 4.78, CI 1.45-15.74] and tachycardia (aOR 2.97, CI 1.22-7.26) were associated with an increased risk of readmission. Sixty-six patients (36%) died after discharge. Risk of death was increased in older patients (aOR 1.32, CI 1.13-1.54 per 5 years), those with peripheral vascular disease (aOR 12.56, CI 2.35-67.21), higher Charlson co-morbidity index (aOR 1.39, CI 1.09-1.76), use of home oxygen (aOR 4.03, CI 1.89-8.57), and those who had been readmitted (aOR 3.07, CI 1.46-6.43).
conclusionsHospitalization for HRF is associated with a high morbidity and mortality. Our observation that home oxygen use was associated with increased mortality suggests that oxygen use could be a risk factor for death in patients with HRF.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.