Evidence map›Paper›PMID 31828510›Full record

ArticleArchives of virology2020

Genetic characterization of a novel recombinant echovirus 30 strain causing a regional epidemic of aseptic meningitis in Hokkaido, Japan, 2017.

Masahiro Miyoshi, Akiko Goto, Rika Komagome, Hiroki Yamaguchi, Yuji Maruo, Masanori Nakanishi, Setsuko Ishida, Hideki Nagano, Takahisa Sugisawa, Motohiko Okano

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Archives of virology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Masahiro MiyoshiHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan. miyo@iph.pref.hokkaido.jp.ORCID http://orcid.org/0000-0003-1645-6646
Akiko GotoHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.
Rika KomagomeHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.
Hiroki YamaguchiHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.
Yuji MaruoDepartment of Pediatrics, Kushiro Red Cross Hospital, 21-14, Shinei-cho, Kushiro, 085-8512, Japan.
Masanori NakanishiDepartment of Pediatrics, Kushiro Red Cross Hospital, 21-14, Shinei-cho, Kushiro, 085-8512, Japan.
Setsuko IshidaHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.
Hideki NaganoHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.
Takahisa SugisawaKushiro Center of Public Health, 4-22, Shiroyama 2, Kushiro, 085-0826, Japan.
Motohiko OkanoHokkaido Institute of Public Health, North 19 West 12, Kita-ku, Sapporo, 060-0819, Japan.

Funding

The Hokkaido Government Grant-in-Aid for scientific research
6 · The paper itself

Abstract

A regional epidemic of aseptic meningitis caused by echovirus 30 (E30) occurred in Hokkaido, Japan, during the period of August-December 2017. To investigate their phylogenetic relationship to other human enteroviruses, we determined the complete genomic nucleotide sequences of isolates from this outbreak. Phylogenetic analysis of the viral capsid protein 1 gene showed that the strains were most closely related to E30 strains detected in Germany, France, and Russia in 2013. In contrast, the region encoding the viral protease and the RNA-dependent RNA polymerase had a close phylogenetic relationship to non-E30 enteroviruses detected in the United Kingdom and Switzerland in 2015-2017, suggesting that a recombination event had occurred.

Indexed as

Capsid ProteinsDisease OutbreaksEchovirus InfectionsEnterovirus B, HumanEnterovirus InfectionsEpidemicsFranceGenotypeGermanyHumansJapanMeningitis, AsepticMolecular EpidemiologyPhylogenyRNA, ViralRussiaCapsid ProteinsRNA, ViralAseptic meningitisEchovirus 30Genetic characterizationGenome recombinationOutbreak

Identifiers

PMID31828510
PMCPMC7223842

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.