Evidence map›Paper›PMID 31828490›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2020

Effects of an exercise-based oncology rehabilitation program and age on strength and physical function in cancer survivors.

Kim Dittus, Michael Toth, Jeff Priest, Patricia O'Brien, Nathan Kokinda, Philip Ades

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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  8. Evaluation by electronic patient-reported outcomes of cancer survivors' needs and the efficacy of inpatient cancer rehabilitation in different tumor entities.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Kim DittusDepartment of Internal Medicine, Vermont Center on Behavior and Health, University of Vermont, Given E-214, 89 Beaumont Ave, Burlington, VT, 05405, USA. kim.dittus@vtmednet.org.
Michael TothDepartments of Internal Medicine and Molecular Physiology and Biophysics, College of Medicine, University of Vermont, Burlington, VT, USA.
Jeff PriestMedical Biostatistics Unit, University of Vermont, Burlington, VT, 05405, USA.
Patricia O'BrienDepartment of Internal Medicine, University of Vermont, Burlington, VT, USA.
Nathan KokindaDepartment of Rehabilitation and Movement Science, University of Vermont, Burlington, VT, USA.
Philip AdesDepartment of Internal Medicine, Vermont Center on Behavior and Health, University of Vermont, Given E-214, 89 Beaumont Ave, Burlington, VT, 05405, USA.
University of Vermont · USUniversity of Vermont Medical Center · US

Funding

Vermont Center on Behavior and HealthP20GM103644 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI SIGMON, STACEY C · 2013 to 2022
$21.3M
Skeletal Muscle Atrophy and Dysfunction in Human CancerR01AR065826 · NIAMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI TOTH, MICHAEL J · 2016 to 2021
$2.1M
Alternative exercise modalities to improve skeletal muscle function in cancer survivorsR21CA191532 · NCI · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI TOTH, MICHAEL J · 2016 to 2017
$371k
National Institute of Health P20GM103644NCI NIH HHS R21 CA191532NIAMS NIH HHS R01 AR065826NIGMS NIH HHS P20 GM103644
6 · The paper itself

Abstract

purposeCancer therapy diminishes strength and physical function in cancer survivors. Whether oncology rehabilitation (OR) exercise training following therapy can correct these deficits, and whether its effectiveness differs by age, is not clear. We examine the utility of a clinically based, 12-week, combined aerobic and resistance training intervention on muscle strength and physical function in two age groups of cancer survivors.

methodsStrength and physical function measures were assessed in middle-aged (45 to 64 years) and older (≥ 65 years) patients following treatment for stage 0-III cancer before and after the OR training program.

resultsOlder patients had lower physical function compared to middle-aged patients across a range of subjective and objective measures at baseline, and exercise improved all indices of physical function and strength in both age groups. Compared to the middle-aged individuals, older participants tended to have less improvement leg strength and the 5 time sit to stand (5TSTS) test as a result of OR. In models predicting post-intervention measures, older age contributed to less improvement in walking distance and power as well as the 5TSTS test.

conclusionPrior to beginning the OR exercise program, middle-aged patients had higher physical function compared to older patients. However, a 12-week aerobic and resistance training intervention improved physical function across both age groups, although older age did limit responsiveness in some physical function measures. The physical function and strength of middle-aged and older cancer survivors improve in response to an exercise-based OR program after cancer treatment.

Indexed as

AgedAge FactorsCancer SurvivorsExerciseExercise TherapyFemaleHumansMaleMiddle AgedMuscle StrengthNeoplasmsResistance TrainingAgeCancer survivorFunctionStrength

Identifiers

PMID31828490
PMCPMC8185895
OpenAlexW2996686820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.