Evidence map›Paper›PMID 31828452›Full record

ArticleOral and maxillofacial surgery2020

A mucinous adenocarcinoma of the lip with elevated serum carcinoembryonic antigen levels: a case report.

Takayuki Aoki, Yusuke Kondo, Kazunari Karakida, Hiroyuki Naito, Hiroshi Kajiwara, Yoshihide Ota

Abstract readCase Reports
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In one paragraph

Article in Oral and maxillofacial surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

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2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Takayuki AokiDepartment of Oral and Maxillofacial Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. taoki123jp@ybb.ne.jp.ORCID http://orcid.org/0000-0003-1850-3469
Yusuke KondoDepartment of Pathology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Kazunari KarakidaDepartment of Oral and Maxillofacial Surgery, Tokai University Hachioji Hospital, 1838 Ishikawamachi, Hachioji, Tokyo, 192-0032, Japan.
Hiroyuki NaitoDepartment of Oral and Maxillofacial Surgery, Iwaki City Medical Center, 16 Uchigo-Mimayamachi-Kusehara, Iwaki, Fukushima, 973-8555, Japan.
Hiroshi KajiwaraDepartment of Pathology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Yoshihide OtaDepartment of Oral and Maxillofacial Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Tokai University · JPTokai University Hachioji Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMucinous adenocarcinoma (MAC) rarely occurs in the salivary glands, especially in the labial gland. MACs arising from the salivary glands are characterized by an aggressive behavior due to high invasiveness and a high rate of regional lymph node metastasis. CASE PRESENTATION: Here, we report a case of MAC arising from the lower lip, shown to have elevated serum carcinoembryonic antigen (CEA) levels by the medical checkup. The tumor showed aggressive behavior and serum CEA levels increased with repeated recurrence. CEA has been shown to have surprisingly diverse functions in cell adhesion, intracellular and intercellular signaling, and complex biological processes such as cancer progression, inflammation, angiogenesis, and metastasis. A MAC arising from the salivary glands may have a poor prognosis because CEA is highly expressed.

conclusionsGenerally, serum CEA levels have not been used as tumor markers for salivary gland malignancies; however, it may be useful for MAC arising from salivary glands. We recommend prospective research to determine whether serum CEA estimation is useful as a component of routine pre-treatment workup for MACs arising from the salivary glands.

Indexed as

Adenocarcinoma, MucinousBiomarkers, TumorCarcinoembryonic AntigenHumansLipNeoplasm Recurrence, LocalPrognosisProspective StudiesBiomarkers, TumorCarcinoembryonic AntigenCarcinoembryonic antigenLipMucinous adenocarcinomaSalivary glandTumor marker

Identifiers

PMID31828452
OpenAlexW2996544936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.