Evidence map›Paper›PMID 31828241›Full record

ArticleTurkish journal of anaesthesiology and reanimation2019

Effects of Inadvertent Perioperative Hypothermia on Metabolic and Inflammatory Mediators.

Halide Aydın, Tuncer Şimşek, Yavuz Demiraran

Registry-linked trialAbstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05469958 (Efficacy of Perioperative Hypothermia Prevention Measures in Osteosynthesis. Clinical Trial With Control Group and Validation Into Spanish of the "BEDSIDE SHIVERING ASSESSMENT SCALE".), which is not on this map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05469958 nacompletednot on this mapstarted 2022, after this paper: background citation

Efficacy of Perioperative Hypothermia Prevention Measures in Osteosynthesis. Clinical Trial With Control Group and Validation Into Spanish of the "BEDSIDE SHIVERING ASSESSMENT SCALE".

TypeinterventionalSponsorUniversitat Internacional de CatalunyaRan2022 to 2024Enrolled148ConditionsHypothermia, Hypothermia, Accidental, Hypothermia, AnesthesiaArmsHypothermia prevention bundle, Conventional care
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Halide AydınClinic of Anaesthesiology and Reanimation, Van Training and Research Hospital, Van, Turkey.ORCID https://orcid.org/0000-0002-7091-3505
Tuncer ŞimşekDepartment of Anaesthesiology and Reanimation, Çanakkale Onsekiz Mart University School of Medicine, Çanakkale, Turkey.ORCID https://orcid.org/0000-0001-8035-7509
Yavuz DemiraranDeparment of Anaesthesiology and Reanimation, Medipol University School of Medicine, İstanbul, Turkey.ORCID https://orcid.org/0000-0003-0811-4945

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of the present study was to investigate the effects of perioperative undesirable hypothermia on inflammatory (interleukin (IL)-8, IL-10, IL-18, IL-23 and pentraxin (PTX)-3) and metabolic responses (cortisol and insulin) and recovery time.

methodsA total of 60 patients between the ages of 18 and 65 years who were in the lumbar stabilisation operation were included in the study. In this prospective, randomised controlled study, two groups were constituted as with warmed (Group N) and not warmed (Group C) patients before and during the operation. Diuresis, blood loss, body temperature and side effects were recorded with IL-8, IL-10, IL-18, IL-23, PTX-3, cortisol and insulin levels.

resultsPerioperative diuresis was significantly higher in Group C. Aldrete score was significantly higher in Group N with less shivering and vomiting in the postoperative period. IL-10, PTX-3 and cortisol levels were found to be significantly higher in Group C in the first postoperative hour. PTX-3 and cortisol were found to be significantly higher in Group C after 24 h of the operation. Insulin was significantly higher in Group N. In 72 h, IL-8 in Group N and cortisol level in Group C were significantly higher.

conclusionPositive effects of heating the patients in the perioperative period on haemorrhage, diuresis, complications and recovery time were observed in our study. In addition, maintenance of normothermia appeared to modulate the biomarkers that indicate the inflammatory and metabolic responses.

Indexed as

Cortisolhypothermiainflammation mediatorsinsulin

Identifiers

PMID31828241
PMCPMC6886828

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.