Evidence map›Paper›PMID 31828207›Full record

ArticleAddictive behaviors reports2019

Comparing Alcohol Use Disorders Identification Test (AUDIT) with Timeline Follow Back (TLFB), DSM-5 and Phosphatidylethanol (PEth) for the assessment of alcohol misuse among young people in Ugandan fishing communities.

Monica O Kuteesa, Sarah Cook, Helen A Weiss, Anatoli Kamali, Wolfgang Weinmann, Janet Seeley, Josephine N Ssentongo, Thaddeus Kiwanuka, Florence Namyalo, Denis Nsubuga and 1 more

Abstract read
In one paragraph

Article in Addictive behaviors reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

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0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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  14. AUDIT C compared to PEth in middle-aged volunteers.Alcohol and alcoholism (Oxford, Oxfordshire) · 2024
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Monica O KuteesaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Sarah CookDepartment of Non-Communicable Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Helen A WeissMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.
Anatoli KamaliInternational AIDS Vaccine Initiative (IAVI), Nairobi, Kenya.
Wolfgang WeinmannDepartment of Forensic Toxicology and Chemistry, Institute for Research Medicine, University of Bern, Switzerland.
Janet SeeleyMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Josephine N SsentongoMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Thaddeus KiwanukaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Florence NamyaloMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Denis NsubugaMRC/UVRI and LSHTM Uganda Research Unit, Entebbe, Uganda.
Emily L WebbMRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, UK.

Funding

Medical Research Council MR/R010161/1
6 · The paper itself

Abstract

backgroundValidated tools for assessing alcohol use among young people in low-income countries are needed to estimate prevalence and evaluate alcohol-reduction interventions. We validated Alcohol Use Disorders Identification Test (AUDIT) against Timeline Follow Back (TLFB), Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and phosphatidylethanol (PEth); and the 30-day-AUDIT against the 12-months-AUDIT among young Ugandans.

methodsIn 2018, we collected retrospective data on 30-day and 12-month AUDIT, TLFB and DSM-5 in a cross-sectional study of 15-24 year old residents of Ugandan fishing communities. AUDIT was administered by Audio Computer Assisted Self-Interviewing (ACASI) and DSM-5 and TLFB by psychiatric nurses. We determined PEth16:0/18:1 levels from dried blood spots using liquid chromatography tandem-mass spectrometry (heavy usage, ≥210 ng/mL) and calculated sensitivity and specificity of AUDIT against the other measures.

resultsAmong 1281 participants (52.7% male, mean age 20 years), half (n = 659; 51.4%) reported ever drinking alcohol, 19.4% had 12-month-AUDIT ≥ 8 (21.5% men; 17.0% women), and 24.2% had 30-day-AUDIT ≥ 8 (29.0% men; 18.9% women). Twenty percent of participants had detectable PEth with 55 (4.3%) classified as heavy drinkers; 50.7% reported ≥ 2 symptoms on DSM-5 and 6.3% reported binge drinking in the previous month based on TLFB (8.9% men, 3.5% women). The 30-day-AUDIT ≥ 8 had sensitivity 86.7%, 95%CI: 81.8%-90.7% and specificity 90.9%, 95%CI:89.0%-92.6% versus 12-month-AUDIT ≥ 8. Both 30-day and 12-month-AUDIT ≥ 8 were sensitive and specific markers of heavy drinking by PEth (12-month-AUDIT sensitivity = 80.0%; 95%CI:67.0%-89.6%; specificity = 83.3%; 95%CI:81.1%-85.3%). The 30-day-AUDIT was a sensitive and specific marker of binge drinking based on TLFB (sensitivity = 82.7%; 95%CI:72.7%-90.2%, specificity = 79.8%; 95%CI:77.4%-82.1%); 12-month-AUDIT had lower sensitivity. Both 30-day and 12-month AUDIT ≥ 8 were highly specific but insensitive markers of having DSM-5 ≥ 2 symptoms.

conclusionAmong young people in Uganda, ACASI-administered 30-day and 12-month-AUDIT have good diagnostic properties compared to PEth, DSM-5 and TLFB. Self-reported AUDIT provides a quick and valid means of assessing alcohol misuse in these communities.

Identifiers

PMID31828207
PMCPMC6888770

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.