Evidence map›Paper›PMID 31828118›Full record

SynthesisBioMed research international2019

Optical Coherence Tomography Angiography Assessed Retinal and Choroidal Microvasculature Features in Patients with Retinitis Pigmentosa: A Meta-Analysis.

Ling Ling, Feifei Gao, Qinglin Zhang, Tao He, Yi Zhao, Yiqiao Xing, Yifeng Yu, Kaibao Ji

Abstract readMeta-AnalysisReview
In one paragraph

Synthesis in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Optical coherence tomography angiography (OCT-A) in retinitis pigmentosa and macular dystrophy patients: a retrospective study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022
    Article
  11. Article
  12. Optical coherence tomography angiography findings in patients undergoing transcorneal electrical stimulation for treating retinitis pigmentosa.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  13. The impact of macular edema on microvascular and metabolic alterations in retinitis pigmentosa.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2021
    Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ling LingAffiliated Eye Hospital of Nanchang University, Nanchang, Jiangxi, China.ORCID https://orcid.org/0000-0002-7309-4410
Feifei GaoAffiliated Eye Hospital of Nanchang University, Nanchang, Jiangxi, China.
Qinglin ZhangAffiliated Eye Hospital of Nanchang University, Nanchang, Jiangxi, China.
Tao HeDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yi ZhaoDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yiqiao XingDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.
Yifeng YuDepartment of Ophthalmology, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.ORCID https://orcid.org/0000-0002-6598-2274
Kaibao JiDepartment of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, Hubei, China.ORCID https://orcid.org/0000-0002-7704-8438

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to assess the retinal and choroidal microvasculature features using optical coherence tomography angiography (OCTA) in patients with retinitis pigmentosa (RP).

methodsThis study was a meta-analysis of relevant published studies that were included after a comprehensive search of PubMed, Embase, Cochrane Library, and Web of Science databases. Mean difference (MD) with a 95% confidence interval was used to assess continuous variable outcomes. Heterogeneity was evaluated using the chi-squared test based on the values of

resultsSeven studies were included in this meta-analysis. The vessel density values measured in the superficial and deep foveal zones of RP patients using OCTA were significantly lower than the recorded values in the control groups (MD = -3.58,

conclusionsWe showed that retinal and choroidal vessels were attenuated in RP patients. Additionally, we revealed that the FAZ was larger in RP patients, especially the deep FAZ. OCTA may become a useful modality in the diagnosis and monitoring of patients with RP.

Indexed as

AngiographyTomography, Optical CoherenceAdultAgedChoroidFemaleHumansMaleMicrovesselsMiddle AgedRetinaRetinal VesselsRetinitis PigmentosaYoung Adult

Identifiers

PMID31828118
PMCPMC6881583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.