ReviewJournal of lifestyle medicine2019
Impact of Early Life or Intrauterine Factors and Socio-Economic Interaction on Diabetes - An Evidence on Thrifty Hypothesis.
Review in Journal of lifestyle medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Double Burden of Malnutrition in Rural Madagascar: A Study on Infant Health in Ampefy.Nutrients · 2025Article
- Associations of concurrent early-life famine exposure and adulthood obesity with type 2 diabetes mellitus in middle-aged Chinese.Journal of diabetes · 2024Article
- Birth weight is associated with obesity and T2DM in adulthood among Chinese women.BMC endocrine disorders · 2022Article
- Undernutrition when young and the risk of poor renal function in adulthood in women with diabetes in Shanghai, China.The Journal of international medical research · 2021Article
- Gestational Diabetes in the Arab Gulf Countries: Sitting on a Land-Mine.International journal of environmental research and public health · 2020Review
- Genetic and Environmental Factors Contributing to Visceral Adiposity in Asian Populations.Endocrinology and metabolism (Seoul, Korea) · 2020Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is one of the most concerning non-communicable diseases worldwide. The prevalence of diabetes increased rapidly by the influence of socioeconomic interactions. The thrifty hypothesis postulates that certain genes that are involved in positive selection promote efficient fat deposition and storage. This is beneficial for the survival of mankind in adverse conditions. However, in this modern society, these genes have become disadvantageous as people are significantly less likely to experience famines and nutrition shortages. The socioeconomic development that has occurred during the 20th century induced abundance of food supplies in almost all regions of the world. This has led to a rapid rise in the prevalence of obesity, and type 2 diabetes as a consequence. Boom of diabetic pandemic in newly developed countries compare with others those who developed gradually can be explain by thrifty hypothesis, as a result of the difference in the exposure to environmental factors and famine by the ancestors leads. The globalization, urbanization, lack of physical activity, intake of high calorie food and migration is major cause of pandemic emergence of diabetes in high as well as middle and low-income countries.
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Registered trials
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