Evidence map›Paper›PMID 31828019›Full record

ReviewSchizophrenia research. Cognition2020

Metacognitive function and fragmentation in schizophrenia: Relationship to cognition, self-experience and developing treatments.

Paul H Lysaker, Kyle S Minor, John T Lysaker, Ilanit Hasson-Ohayon, Kelsey Bonfils, Jesse Hochheiser, Jenifer L Vohs

Open access · goldAbstract readReview
In one paragraph

Review in Schizophrenia research. Cognition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 3 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 3 syntheses or guidelines pooled it, 125 citations in OpenAlex.

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  18. Metacognition impairment in stroke.Frontiers in neurology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 2 countries.

Paul H LysakerRoudebush Veteran Affairs Medical Center, Indiana University School of Medicine, Indianapolis, IN, USA.
Kyle S MinorIndiana University-Purdue University at Indianapolis, Indianapolis, IN, USA.
John T LysakerEmory University, Atlanta, GA, USA.
Ilanit Hasson-OhayonBar Ilan University, Israel.
Kelsey BonfilsVA Pittsburgh Healthcare System, Mental Illness Research, Education, & Clinical Center (MIRECC), Pittsburgh, PA, USA.
Jesse HochheiserUniversity of Nebraska-Lincoln, Lincoln, NE, USA.
Jenifer L VohsIndiana University School of Medicine, Indianapolis, IN, USA.
Bar-Ilan University · ILEmory University · USIndiana University School of MedicineRichard L. Roudebush VA Medical Center · USUniversity of Indianapolis · USUniversity of Nebraska–Lincoln · USUniversity of Pittsburgh · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bleuler suggested that fragmentation of thought, emotion and volition were the unifying feature of the disorders he termed schizophrenia. In this paper we review research seeking to measure some of the aspects of fragmentation related to the experience of the self and others described by Bleuler. We focus on work which uses the concept of metacognition to characterize and quantify alterations or decrements in the processes by which fragments or pieces of information are integrated into a coherent sense of self and others. We describe the rationale and support for one method for quantifying metacognition and its potential to study the fragmentation of a person's sense of themselves, others and the relative place of themselves and others in the larger human community. We summarize research using that method which suggests that deficits in metacognition commonly occur in schizophrenia and are related to basic neurobiological indices of brain functioning. We also present findings indicating that the capacity for metacognition in schizophrenia is positively related to a broad range of aspects of psychological and social functioning when measured concurrently and prospectively. Finally, we discuss the evolution and study of one therapy that targets metacognitive capacity, Metacognitive Reflection and Insight Therapy (MERIT) and its potential to treat fragmentation and promote recovery.

Indexed as

InsightMetacognitionNeurocognitionRecoveryRehabilitationSchizophrenia

Identifiers

PMID31828019
PMCPMC6889776
OpenAlexW2940882560

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.